SCHEMBL17943393

SCHEMBL17943393

c1ccc(-c2nc(-c3ccc(-c4ccc(-n5c6ccccc6c6ccccc65)cc4)cc3)nc(-c3cc4ccccc4c4ccccc34)n2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ATM Q13315 2/20 0.45
▸ KDM4E B2RXH2 2/20 0.45
▸ L3MBTL1 Q9Y468 1/20 0.45
▸ CYP11B1 P15538 1/20 0.39
▸ HDAC4 P56524 1/20 0.38
▸ KMT2A Q03164 5/20 0.36
▸ MEN1 O00255 3/20 0.36
▸ MAPT P10636 3/20 0.36
▸ ALDH1A1 P00352 1/20 0.36
▸ HPGD P15428 1/20 0.36
▸ AKR1C4 P17516 1/20 0.35
▸ AKR1C3 P42330 1/20 0.35
▸ AKR1C2 P52895 1/20 0.35
▸ AKR1C1 Q04828 1/20 0.35
▸ ALOX5 P09917 1/20 0.35
▸ RXRA P19793 1/20 0.35
▸ GPR84 Q9NQS5 1/20 0.35
▸ AVPR1A P37288 1/20 0.34
▸ HSP90AA1 P07900 1/20 0.34
▸ PTPN1 P18031 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21191468 0.99 ATM (0.46) ATMKDM4EL3MBTL1CYP11B1HDAC4
SCHEMBL17943447 0.97 KDM4E (0.43) ATMKDM4EL3MBTL1CYP11B1HDAC4
SCHEMBL24152638 0.95 KDM4E (0.41) ATMKDM4EL3MBTL1CYP11B1HDAC4
SCHEMBL24152883 0.94 ATM (0.40) ATMKDM4EL3MBTL1CYP11B1HDAC4
SCHEMBL23336203 0.93 KDM4E (0.46) ATMKDM4EL3MBTL1CYP11B1HDAC4
SCHEMBL21191449 0.92 KDM4E (0.44) ATMKDM4EL3MBTL1CYP11B1HDAC4
SCHEMBL21191476 0.92 KDM4E (0.44) ATMKDM4EL3MBTL1CYP11B1HDAC4
SCHEMBL24152729 0.91 KDM4E (0.41) ATMKDM4EL3MBTL1CYP11B1KMT2A
SCHEMBL21191453 0.91 KDM4E (0.45) ATMKDM4EL3MBTL1CYP11B1HDAC4
SCHEMBL23336043 0.91 KDM4E (0.41) ATMKDM4EL3MBTL1CYP11B1HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11737354-B2 Organic light emitting device having a carbazole-based compound formed between a cathode and a light emitting layer and a spirobifluorene-monoamine-based compound formed between an anode and a light emitting layer LG CHEM, LTD. (KR) 2023-08-22 — — US disclosed
US-11737354-B2 Organic light emitting device having a carbazole-based compound formed between a cathode and a light emitting layer and a spirobifluorene-monoamine-based compound formed between an anode and a light emitting layer LG CHEM, LTD. (KR) 2023-08-22 — — US disclosed
WO-2021261962-A1 ORGANIC LIGHT-EMITTING DEVICE 주식회사 엘지화학 2021-12-30 — — WO disclosed
WO-2021261907-A1 ORGANIC LIGHT EMITTING DEVICE 주식회사 엘지화학 2021-12-30 — — WO disclosed
WO-2021261977-A1 ORGANIC LIGHT-EMITTING DEVICE 주식회사 엘지화학 2021-12-30 — — WO disclosed
US-20200295264-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2020-09-17 — — US disclosed
US-10714692-B2 Organic light emitting device having a carbazole-based compound formed between cathode and light emitting layer and a spirobifluorene-monoamine based compound formed between anode and light emitting layer LG CHEM, LTD. (KR) 2020-07-14 — — US disclosed
WO-2019143223-A9 POLYCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DIODE COMPRISING SAME 주식회사 엘지화학 2020-04-16 — — WO disclosed
WO-2019143223-A1 POLYCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DIODE COMPRISING SAME 주식회사 엘지화학 2019-07-25 — — WO disclosed
US-9595679-B2 Organic light emitting diode LG CHEM, LTD. (KR) 2017-03-14 — — US disclosed
US-9595679-B2 Organic light emitting diode LG CHEM, LTD. (KR) 2017-03-14 — — US disclosed
US-20160276594-A1 ORGANIC LIGHT EMITTING DIODE LG CHEM, LTD. (KR) 2016-09-22 — — US disclosed
US-20160276594-A1 ORGANIC LIGHT EMITTING DIODE LG CHEM, LTD. (KR) 2016-09-22 — — US disclosed
US-20160225993-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2016-08-04 — — US disclosed
US-20160225993-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2016-08-04 — — US disclosed
US-20160218288-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2016-07-28 — — US disclosed
US-20160218288-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2016-07-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200295264-A1 ORGANIC LIGHT EMITTING DEVICE TPH1, DRD1, CYP1A1 ATM 2503/4885KDM4E 2126/4885L3MBTL1 2025/4885
US-10714692-B2 Organic light emitting device having a carbazole-based compound formed between cathode and light emitting layer and a spirobifluorene-monoamine based compound formed between anode and light emitting layer COMT, MAOB, MAOA ATM 641/4885KDM4E 2523/4885L3MBTL1 1067/4885
US-20160276594-A1 ORGANIC LIGHT EMITTING DIODE CRY1, CRY2, NR2E3 ATM 1728/4885KDM4E 2742/4885L3MBTL1 12/4885
US-11737354-B2 Organic light emitting device having a carbazole-based compound formed between a cathode and a light emitting layer and a spirobifluorene-monoamine-based compound formed between an anode and a light emitting layer DRD1, TPH1, DRD3 ATM 1444/4885KDM4E 2285/4885L3MBTL1 1918/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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