SCHEMBL17943396

SCHEMBL17943396

c1ccc2cc3c(cc2c1)c1ccccc1n3-c1ccc(-c2ccc(-c3nc(-c4ccc(-c5cccc6ccccc56)cc4)nc(-c4ccc(-c5cccc6ccccc56)cc4)n3)cc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 2/20 0.38
▸ ATM Q13315 2/20 0.38
▸ L3MBTL1 Q9Y468 2/20 0.38
▸ CA12 O43570 2/20 0.38
▸ CA1 P00915 2/20 0.38
▸ CA2 P00918 2/20 0.38
▸ CA9 Q16790 2/20 0.38
▸ HDAC8 Q9BY41 1/20 0.37
▸ HDAC6 Q9UBN7 1/20 0.37
▸ ALK Q9UM73 1/20 0.37
▸ TUBB4A P04350 1/20 0.36
▸ TUBB P07437 1/20 0.36
▸ TUBA3C P0DPH7 1/20 0.36
▸ TUBA1B P68363 1/20 0.36
▸ TUBA4A P68366 1/20 0.36
▸ TUBB4B P68371 1/20 0.36
▸ TUBB3 Q13509 1/20 0.36
▸ TUBB2A Q13885 1/20 0.36
▸ TUBB8 Q3ZCM7 1/20 0.36
▸ TUBA3E Q6PEY2 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17943379 0.98 KDM4E (0.40) KDM4EATML3MBTL1CA12CA1
SCHEMBL24152098 0.96 KDM4E (0.41) KDM4EATML3MBTL1CA12CA1
SCHEMBL24474642 0.94 KDM4E (0.39) KDM4EATML3MBTL1HDAC8HDAC6
SCHEMBL25605851 0.93 KDM4E (0.40) KDM4EATML3MBTL1CA12CA1
SCHEMBL24153806 0.92 KDM4E (0.43) KDM4EATML3MBTL1CA12CA1
SCHEMBL17943365 0.92 KDM4E (0.44) KDM4EATML3MBTL1CA12CA1
SCHEMBL25605613 0.91 KDM4E (0.41) KDM4EATML3MBTL1TUBB4ATUBB
SCHEMBL25605758 0.91 KDM4E (0.38) KDM4EATML3MBTL1CA12CA1
SCHEMBL22883677 0.90 KDM4E (0.36) KDM4EATML3MBTL1HDAC8HDAC6
SCHEMBL22884161 0.90 KDM4E (0.36) KDM4EATML3MBTL1HDAC8HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11737354-B2 Organic light emitting device having a carbazole-based compound formed between a cathode and a light emitting layer and a spirobifluorene-monoamine-based compound formed between an anode and a light emitting layer LG CHEM, LTD. (KR) 2023-08-22 — — US disclosed
US-11737354-B2 Organic light emitting device having a carbazole-based compound formed between a cathode and a light emitting layer and a spirobifluorene-monoamine-based compound formed between an anode and a light emitting layer LG CHEM, LTD. (KR) 2023-08-22 — — US disclosed
US-20200295264-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2020-09-17 — — US disclosed
US-10714692-B2 Organic light emitting device having a carbazole-based compound formed between cathode and light emitting layer and a spirobifluorene-monoamine based compound formed between anode and light emitting layer LG CHEM, LTD. (KR) 2020-07-14 — — US disclosed
US-9595679-B2 Organic light emitting diode LG CHEM, LTD. (KR) 2017-03-14 — — US disclosed
US-9595679-B2 Organic light emitting diode LG CHEM, LTD. (KR) 2017-03-14 — — US disclosed
US-20160276594-A1 ORGANIC LIGHT EMITTING DIODE LG CHEM, LTD. (KR) 2016-09-22 — — US disclosed
US-20160276594-A1 ORGANIC LIGHT EMITTING DIODE LG CHEM, LTD. (KR) 2016-09-22 — — US disclosed
US-20160225993-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2016-08-04 — — US disclosed
US-20160225993-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2016-08-04 — — US disclosed
US-20160218288-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2016-07-28 — — US disclosed
US-20160218288-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2016-07-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200295264-A1 ORGANIC LIGHT EMITTING DEVICE TPH1, DRD1, CYP1A1 KDM4E 2126/4885ATM 2503/4885L3MBTL1 2025/4885
US-10714692-B2 Organic light emitting device having a carbazole-based compound formed between cathode and light emitting layer and a spirobifluorene-monoamine based compound formed between anode and light emitting layer COMT, MAOB, MAOA KDM4E 2523/4885ATM 641/4885L3MBTL1 1067/4885
US-20160276594-A1 ORGANIC LIGHT EMITTING DIODE CRY1, CRY2, NR2E3 KDM4E 2742/4885ATM 1728/4885L3MBTL1 12/4885
US-11737354-B2 Organic light emitting device having a carbazole-based compound formed between a cathode and a light emitting layer and a spirobifluorene-monoamine-based compound formed between an anode and a light emitting layer DRD1, TPH1, DRD3 KDM4E 2285/4885ATM 1444/4885L3MBTL1 1918/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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