SCHEMBL17943397

SCHEMBL17943397

c1ccc(-c2ccc(-c3nc(-c4ccccc4)cc(-c4ccc(-c5ccc(-n6c7ccccc7c7c8ccccc8ccc76)cc5)cc4)n3)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 8/20 0.42
▸ MEN1 O00255 7/20 0.42
▸ MAPT P10636 7/20 0.42
▸ ALDH1A1 P00352 6/20 0.42
▸ HPGD P15428 6/20 0.42
▸ NTSR1 P30989 1/20 0.42
▸ PTGES O14684 2/20 0.40
▸ KDM4E B2RXH2 5/20 0.39
▸ ATM Q13315 1/20 0.38
▸ L3MBTL1 Q9Y468 1/20 0.38
▸ LMNA P02545 2/20 0.38
▸ GLA P06280 1/20 0.38
▸ ADORA2A P29274 1/20 0.37
▸ ADORA1 P30542 1/20 0.37
▸ MAPK1 P28482 1/20 0.37
▸ TDP1 Q9NUW8 1/20 0.37
▸ CYP1A1 P04798 1/20 0.37
▸ CYP1B1 Q16678 1/20 0.37
▸ NPSR1 Q6W5P4 2/20 0.36
▸ RXFP1 Q9HBX9 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13086753 0.99 KMT2A (0.43) KMT2AMEN1MAPTALDH1A1HPGD
SCHEMBL21577617 0.99 KMT2A (0.43) KMT2AMEN1MAPTALDH1A1HPGD
SCHEMBL22211945 0.94 MAPT (0.40) KMT2AMEN1MAPTALDH1A1HPGD
SCHEMBL22223539 0.94 MAPT (0.40) KMT2AMEN1MAPTALDH1A1HPGD
SCHEMBL19266893 0.94 KMT2A (0.41) KMT2AMEN1MAPTALDH1A1HPGD
SCHEMBL19266690 0.94 KMT2A (0.41) KMT2AMEN1MAPTALDH1A1HPGD
SCHEMBL19266899 0.94 KMT2A (0.41) KMT2AMEN1MAPTALDH1A1HPGD
SCHEMBL19266693 0.94 KMT2A (0.41) KMT2AMEN1MAPTALDH1A1HPGD
SCHEMBL17178812 0.94 HPGD (0.45) KMT2AMEN1MAPTALDH1A1HPGD
SCHEMBL18088932 0.94 HPGD (0.45) KMT2AMEN1MAPTALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11737354-B2 Organic light emitting device having a carbazole-based compound formed between a cathode and a light emitting layer and a spirobifluorene-monoamine-based compound formed between an anode and a light emitting layer LG CHEM, LTD. (KR) 2023-08-22 — — US disclosed
US-11737354-B2 Organic light emitting device having a carbazole-based compound formed between a cathode and a light emitting layer and a spirobifluorene-monoamine-based compound formed between an anode and a light emitting layer LG CHEM, LTD. (KR) 2023-08-22 — — US disclosed
US-20200295264-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2020-09-17 — — US disclosed
US-10714692-B2 Organic light emitting device having a carbazole-based compound formed between cathode and light emitting layer and a spirobifluorene-monoamine based compound formed between anode and light emitting layer LG CHEM, LTD. (KR) 2020-07-14 — — US disclosed
US-9595679-B2 Organic light emitting diode LG CHEM, LTD. (KR) 2017-03-14 — — US disclosed
US-9595679-B2 Organic light emitting diode LG CHEM, LTD. (KR) 2017-03-14 — — US disclosed
US-20160276594-A1 ORGANIC LIGHT EMITTING DIODE LG CHEM, LTD. (KR) 2016-09-22 — — US disclosed
US-20160276594-A1 ORGANIC LIGHT EMITTING DIODE LG CHEM, LTD. (KR) 2016-09-22 — — US disclosed
US-20160225993-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2016-08-04 — — US disclosed
US-20160225993-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2016-08-04 — — US disclosed
US-20160218288-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2016-07-28 — — US disclosed
US-20160218288-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2016-07-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200295264-A1 ORGANIC LIGHT EMITTING DEVICE TPH1, DRD1, CYP1A1 KMT2A 755/4885MEN1 594/4885MAPT 1556/4885
US-10714692-B2 Organic light emitting device having a carbazole-based compound formed between cathode and light emitting layer and a spirobifluorene-monoamine based compound formed between anode and light emitting layer COMT, MAOB, MAOA KMT2A 563/4885MEN1 1315/4885MAPT 330/4885
US-20160276594-A1 ORGANIC LIGHT EMITTING DIODE CRY1, CRY2, NR2E3 KMT2A 2025/4885MEN1 3266/4885MAPT 497/4885
US-11737354-B2 Organic light emitting device having a carbazole-based compound formed between a cathode and a light emitting layer and a spirobifluorene-monoamine-based compound formed between an anode and a light emitting layer DRD1, TPH1, DRD3 KMT2A 862/4885MEN1 1075/4885MAPT 1656/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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