Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 1/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.38 |
| ▸ | TOP1 | P11387 | 2/20 | 0.37 |
| ▸ | DDX3X | O00571 | 1/20 | 0.37 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 2/20 | 0.35 |
| ▸ | GLS | O94925 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17948786 | 0.81 | KDM4E (0.53) | PTPN1PTGDR2GAAALDH1A1MEN1 | |
| SCHEMBL17949048 | 0.81 | FBP1 (0.37) | ALDH1A1HSD17B10CYP1A2CYP2C9MEN1 | |
| SCHEMBL17949007 | 0.77 | HSD17B3 (0.41) | APPMEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL17948791 | 0.70 | NR4A2 (0.39) | PTPN2PTPN1PTGDR2AOC3TOP1 | |
| SCHEMBL27789562 | 0.69 | KDM4E (0.47) | GAAALDH1A1HSD17B10CYP1A2CYP2C9 | |
| SCHEMBL1258223 | 0.69 | MAPK14 (0.45) | PTGDR2ALDH1A1HSD17B10CYP1A2CYP2C9 | |
| SCHEMBL27834590 | 0.69 | KDM4E (0.44) | GAAALDH1A1HSD17B10CYP1A2CYP2C9 | |
| SCHEMBL980993 | 0.68 | ALDH1A1 (0.47) | GAAALDH1A1HSD17B10CYP1A2MEN1 | |
| SCHEMBL13398494 | 0.68 | KDM4E (0.46) | GAAALDH1A1HSD17B10CYP1A2CYP2C9 | |
| SCHEMBL984151 | 0.68 | MAPK14 (0.41) | PTGDR2ALDH1A1HSD17B10CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230046194-A1 | Ribosome-Mediated Incorporation of Peptides and Peptidomimetics | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2023-02-16 | — | — | US | disclosed |
| US-20200370057-A1 | Ribosome-Mediated Incorporation of Peptides and Peptidomimetics | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2020-11-26 | — | — | US | disclosed |
| US-10745705-B2 | Ribosome-mediated incorporation of peptides and peptidomimetics | ARIZON BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2020-08-18 | — | — | US | disclosed |
| US-20180002709-A1 | RIBOSOME-MEDIATED INCORPORATION OF PEPTIDES AND PEPTIDOMIMETICS | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2018-01-04 | — | — | US | disclosed |
| WO-2016118877-A1 | RIBOSOME-MEDIATED INCORPORATION OF PEPTIDES AND PEPTIDOMIMETICS | ARIZON BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2016-07-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180002709-A1 | RIBOSOME-MEDIATED INCORPORATION OF PEPTIDES AND PEPTIDOMIMETICS | NPEPPS, DNPEP, AARS1 | PTPRC 1967/4885PTPN2 1472/4885PTPN1 1363/4885 |
| US-20200370057-A1 | Ribosome-Mediated Incorporation of Peptides and Peptidomimetics | NPEPPS, DNPEP, AARS1 | PTPRC 1967/4885PTPN2 1472/4885PTPN1 1363/4885 |
| US-20230046194-A1 | Ribosome-Mediated Incorporation of Peptides and Peptidomimetics | NPEPPS, DNPEP, AARS1 | PTPRC 1967/4885PTPN2 1472/4885PTPN1 1363/4885 |
| US-10745705-B2 | Ribosome-mediated incorporation of peptides and peptidomimetics | NPEPPS, DNPEP, AARS1 | PTPRC 1967/4885PTPN2 1472/4885PTPN1 1363/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.