Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 3/20 | 0.31 |
| ▸ | IDH1 | O75874 | 3/20 | 0.31 |
| ▸ | CNR2 | P34972 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17529566 | 0.85 | S1PR1 (0.32) | S1PR1LMNAHTTSMN1; SMN2 | |
| SCHEMBL20997774 | 0.85 | DRD2 (0.30) | DDR1 | |
| SCHEMBL24285909 | 0.83 | — | — | |
| SCHEMBL17844190 | 0.83 | POLB (0.39) | DDR1 | |
| SCHEMBL29904938 | 0.83 | POLB (0.39) | DDR1 | |
| SCHEMBL17529570 | 0.83 | CYP1A2 (0.36) | S1PR1ELANECNR2LMNAHTT | |
| SCHEMBL17941364 | 0.82 | S1PR1 (0.35) | S1PR1KCNH2DDR1ELANECNR2 | |
| SCHEMBL24285908 | 0.82 | — | — | |
| SCHEMBL31534714 | 0.81 | CNR2 (0.35) | S1PR1KCNH2DDR1CNR2LMNA | |
| SCHEMBL18013264 | 0.81 | CNR2 (0.35) | S1PR1KCNH2DDR1CNR2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12134612-B2 | Pesticidally active polycyclic derivatives with sulfur containing substituents | SYNGENTA CROP PROTECTION AG (CH) | 2024-11-05 | — | — | US | disclosed |
| US-20210332039-A1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2021-10-28 | — | — | US | disclosed |
| US-20210332039-A1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2021-10-28 | — | — | US | disclosed |
| US-10981907-B2 | Pesticidally active polycyclic derivatives with sulfur containing substituents | SYNGENTA PARTICIPATIONS AG (CH) | 2021-04-20 | — | — | US | disclosed |
| US-10981907-B2 | Pesticidally active polycyclic derivatives with sulfur containing substituents | SYNGENTA PARTICIPATIONS AG (CH) | 2021-04-20 | — | — | US | disclosed |
| US-20190144445-A1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-05-16 | — | — | US | disclosed |
| US-20190144445-A1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-05-16 | — | — | US | disclosed |
| US-10138238-B2 | Pesticidally active polycyclic derivatives with sulfur containing substituents | SYNGENTA PARTICIPATIONS AG (CH) | 2018-11-27 | — | — | US | disclosed |
| US-20170362224-A1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-12-21 | — | — | US | disclosed |
| US-20170362224-A1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-12-21 | — | — | US | disclosed |
| US-20170362224-A1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-12-21 | — | — | US | disclosed |
| WO-2016116338-A1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-07-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10981907-B2 | Pesticidally active polycyclic derivatives with sulfur containing substituents | DDT, ACHE, GSTM1 | S1PR1 2108/4885KCNH2 2503/4885DDR1 4467/4885 |
| US-12134612-B2 | Pesticidally active polycyclic derivatives with sulfur containing substituents | DDT, ACHE, SQOR | S1PR1 2066/4885KCNH2 2441/4885DDR1 4383/4885 |
| US-20190144445-A1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | DDT, ACHE, SQOR | S1PR1 2066/4885KCNH2 2441/4885DDR1 4383/4885 |
| US-20170362224-A1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | DDT, SQOR, PTMS | S1PR1 2342/4885KCNH2 1928/4885DDR1 4512/4885 |
| US-20210332039-A1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | DDT, ACHE, SQOR | S1PR1 2066/4885KCNH2 2441/4885DDR1 4383/4885 |
| US-10138238-B2 | Pesticidally active polycyclic derivatives with sulfur containing substituents | DDT, SQOR, PTMS | S1PR1 2342/4885KCNH2 1928/4885DDR1 4512/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.