Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.33 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1793511 | 1.00 | MEN1 (0.39) | MEN1GAAKMT2ATDP1MAOA | |
| SCHEMBL17234179 | 1.00 | MEN1 (0.39) | MEN1GAAKMT2ATDP1MAOA | |
| SCHEMBL5490945 | 0.91 | MEN1 (0.43) | MEN1GAAKMT2ATDP1MAOA | |
| SCHEMBL2905985 | 0.91 | MEN1 (0.43) | MEN1GAAKMT2ATDP1MAOA | |
| SCHEMBL18262806 | 0.90 | TDP1 (0.44) | MEN1GAAKMT2ATDP1MAOA | |
| SCHEMBL12514747 | 0.90 | TDP1 (0.44) | MEN1GAAKMT2ATDP1MAOA | |
| SCHEMBL1795152 | 0.90 | TDP1 (0.44) | MEN1GAAKMT2ATDP1MAOA | |
| SCHEMBL20122294 | 0.89 | TDP1 (0.47) | MEN1GAAKMT2ATDP1MAOA | |
| SCHEMBL20191171 | 0.89 | TDP1 (0.47) | MEN1GAAKMT2ATDP1MAOA | |
| SCHEMBL12155283 | 0.89 | TDP1 (0.47) | MEN1GAAKMT2ATDP1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12565498-B2 | β-lactamase inhibitors and their preparation | NINGXIA ACADEMY OF AGRICULTURE AND FORESTRY SCIENCES (CN) | 2026-03-03 | — | — | US | disclosed |
| CN-115151544-B | Beta-lactamase inhibitor and preparation thereof | 宁夏农林科学院 | 2024-08-16 | — | — | CN | disclosed |
| US-20230365561-A1 | BETA-LACTAMASE INHIBITORS AND THEIR PREPARATION | NINGXIA ACADEMY OF AGRICULTURE AND FORESTRY SCIENCES (CN) | 2023-11-16 | — | — | US | disclosed |
| EP-4146650-A1 | BETA-LACTAMASE INHIBITORS AND THEIR PREPARATION | Ningxia Academy of Agriculture and Forestry Sciences (CN) | 2023-03-15 | — | — | EP | disclosed |
| CN-115151544-A | Beta-lactamase inhibitors and preparation thereof | 宁夏农林科学院 | 2022-10-04 | — | — | CN | disclosed |
| WO-2022047603-A1 | BETA-LACTAMASE INHIBITORS AND THEIR PREPARATION | NINGXIA ACADEMY OF AGRICULTURE AND FORESTRY SCIENCES (CN) | 2022-03-10 | — | — | WO | disclosed |
| US-20180371138-A1 | AQUEOUS SYNTHESIS AND IN-SITU RAPID SCREENING OF AMPHIPHILIC POLYMERS | UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (ES) | 2018-12-27 | — | — | US | disclosed |
| EP-3390471-A1 | AQUEOUS SYNTHESIS AND IN-SITU RAPID SCREENING OF AMPHIPHILIC POLYMERS | Universidade De Santiago De Compostela (ES) | 2018-10-24 | — | — | EP | disclosed |
| US-10071975-B2 | Macrocyclic amidinourea derivatives, methods of preparation and uses thereof as chitinase inhibitors | CYGNET BIOSCIENCES B.V. (CW) | 2018-09-11 | — | — | US | disclosed |
| EP-3010896-B1 | NEW MACROCYCLIC AMIDINOUREA DERIVATIVES, METHODS OF PREPARATION AND USES THEREOF AS CHITINASE INHIBITORS | CYGNET BIOSCIENCES B V (CW) | 2017-11-01 | — | — | EP | disclosed |
| EP-3010896-B1 | NEW MACROCYCLIC AMIDINOUREA DERIVATIVES, METHODS OF PREPARATION AND USES THEREOF AS CHITINASE INHIBITORS | CYGNET BIOSCIENCES B V (CW) | 2017-11-01 | — | — | EP | disclosed |
| WO-2017102894-A1 | AQUEOUS SYNTHESIS AND IN-SITU RAPID SCREENING OF AMPHIPHILIC POLYMERS | UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (ES) | 2017-06-22 | — | — | WO | disclosed |
| US-20160137617-A1 | NEW MACROCYCLIC AMIDINOUREA DERIVATIVES, METHODS OF PREPARATION AND USES THEREOF AS CHITINASE INHIBITORS | CYGNET BIOSCIENCES B.V. | 2016-05-19 | — | — | US | disclosed |
| EP-3010896-A1 | NEW MACROCYCLIC AMIDINOUREA DERIVATIVES, METHODS OF PREPARATION AND USES THEREOF AS CHITINASE INHIBITORS | CYGNET BIOSCIENCES B.V. (CW) | 2016-04-27 | — | — | EP | disclosed |
| US-9234007-B2 | RGD mimetic γ-AApeptides and methods of use | UNIVERSITY OF SOUTH FLORIDA (US) | 2016-01-12 | — | — | US | disclosed |
| WO-2014202697-A1 | NEW MACROCYCLIC AMIDINOUREA DERIVATIVES, METHODS OF PREPARATION AND USES THEREOF AS CHITINASE INHIBITORS | BAKKER MEDICAL S.R.L. (IT) | 2014-12-24 | — | — | WO | disclosed |
| WO-2014202697-A1 | NEW MACROCYCLIC AMIDINOUREA DERIVATIVES, METHODS OF PREPARATION AND USES THEREOF AS CHITINASE INHIBITORS | BAKKER MEDICAL S.R.L. (IT) | 2014-12-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160137617-A1 | NEW MACROCYCLIC AMIDINOUREA DERIVATIVES, METHODS OF PREPARATION AND USES THEREOF AS CHITINASE INHIBITORS | CHIT1, CHIA, ENGASE | MEN1 172/4885GAA 75/4885KMT2A 3697/4885 |
| US-10071975-B2 | Macrocyclic amidinourea derivatives, methods of preparation and uses thereof as chitinase inhibitors | CHIT1, CHIA, PEPD | MEN1 185/4885GAA 55/4885KMT2A 3577/4885 |
| US-12565498-B2 | β-lactamase inhibitors and their preparation | PGLS, MGAM, OSTC | MEN1 3421/4885GAA 119/4885KMT2A 2950/4885 |
| US-20230365561-A1 | BETA-LACTAMASE INHIBITORS AND THEIR PREPARATION | MGAM, LCT, GANAB | MEN1 2191/4885GAA 4/4885KMT2A 1197/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.