Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 4/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | CHUK | O15111 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23255442 | 0.97 | KIF11 (0.37) | KIF11DGAT1KCNH2CYP11B2CYP11B1 | |
| SCHEMBL23255422 | 0.93 | CYP11B1 (0.38) | KIF11DGAT1KCNH2CYP11B2CYP11B1 | |
| SCHEMBL23255584 | 0.92 | KIF11 (0.38) | KIF11DGAT1KCNH2CYP11B2CYP11B1 | |
| SCHEMBL23255311 | 0.91 | S1PR1 (0.37) | DGAT1KCNH2CYP11B2CYP11B1PDE10A | |
| SCHEMBL23255314 | 0.89 | KIF11 (0.38) | KIF11CYP11B2PDE10AHTR2BHTR6 | |
| SCHEMBL18374182 | 0.89 | KIF11 (0.49) | KIF11DGAT1KCNH2ALDH1A1MAPT | |
| SCHEMBL23255304 | 0.88 | ABCG2 (0.37) | KIF11CYP11B2CYP11B1HTR2BHTR6 | |
| SCHEMBL17952892 | 0.88 | PIK3CA (0.42) | CYP11B2CYP11B1HTR6DHODHPIK3CA | |
| SCHEMBL23255308 | 0.88 | ICMT (0.37) | KIF11PDE10AHTR2BHTR6MAPT | |
| SCHEMBL23255430 | 0.87 | KIF11 (0.42) | KIF11PDE10AHTR2BHTR6METAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3581570-B1 | CARBAZOLE-PYRIDINE-TRIFLUOROMETHYLPHENYL DERIVATIVES AND RELATED COMPOUNDS FOR USE AS TADF LUMINESCENT EMITTERS IN OLEDS | CYNORA GMBH (DE) | 2021-04-21 | — | — | EP | disclosed |