Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | P2RX4 | Q99571 | 5/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CDK8 | P49336 | 1/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | STK17B | O94768 | 1/20 | 0.33 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17952722 | 0.90 | P2RX4 (0.37) | MAOAMAOBP2RX4CYP1A2CYP2D6 | |
| SCHEMBL21693057 | 0.90 | P2RX4 (0.37) | MAOAMAOBP2RX4CYP1A2CDK8 | |
| SCHEMBL21927306 | 0.86 | UCHL1 (0.39) | MAOAMAOBCYP1A2CDK8HTT | |
| SCHEMBL21927305 | 0.86 | ATR (0.35) | CYP1A2HTTKDM4EALDH1A1 | |
| SCHEMBL21927336 | 0.84 | UCHL1 (0.39) | MAOAMAOBCYP1A2CDK8HTT | |
| SCHEMBL21927334 | 0.84 | ATR (0.36) | MAOAMAOBCYP1A2HTTKDM4E | |
| SCHEMBL17952925 | 0.81 | RPS6KA3 (0.40) | MAOAMAOBP2RX4CYP1A2CYP2D6 | |
| SCHEMBL29534495 | 0.81 | MGLL (0.40) | P2RX4CYP1A2CYP2D6CDK8HTT | |
| SCHEMBL21922119 | 0.81 | NPC1 (0.43) | CYP1A2HTTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL17952780 | 0.80 | MAOA (0.39) | MAOAMAOBCYP1A2CYP2D6CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3247771-B1 | PYRIDINES AND DERIVATIVES THEREOF AS COMPONENTS FOR USE IN OPTOELECTRONIC COMPONENTS | CYNORA GMBH (DE) | 2020-06-10 | — | — | EP | disclosed |
| US-10544361-B2 | Pyridines and derivatives thereof as components for use in optoelectronic components | CYNORA GMBH (DE) | 2020-01-28 | — | — | US | disclosed |
| WO-2016116517-A1 | PYRIDINES AND DERIVATIVES THEREOF AS COMPONENTS FOR USE IN OPTOELECTRONIC COMPONENTS | CYNORA GMBH (DE) | 2016-07-28 | — | — | WO | disclosed |