Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.53 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.53 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5079763 | 0.86 | TDP1 (0.59) | TDP1ALDH1A1TSHRGPR35MAPK1 | |
| SCHEMBL1800029 | 0.84 | GPR35 (0.55) | TDP1ALDH1A1TSHRGPR35MAPK1 | |
| SCHEMBL5962192 | 0.83 | VCAM1 (0.52) | TDP1ALDH1A1TSHRGPR35MAPK1 | |
| SCHEMBL5499188 | 0.82 | TDP1 (0.55) | TDP1ALDH1A1TSHRGPR35MAPK1 | |
| SCHEMBL82629 | 0.82 | VCAM1 (0.66) | TDP1ALDH1A1TSHRGPR35MAPK1 | |
| SCHEMBL7734099 | 0.80 | VCAM1 (0.44) | TDP1ALDH1A1TSHRMAPK1CYP1A2 | |
| SCHEMBL5187586 | 0.78 | GPR35 (0.58) | TDP1ALDH1A1TSHRGPR35MAPK1 | |
| SCHEMBL5202695 | 0.78 | HSD17B10 (0.62) | TDP1ALDH1A1TSHRGPR35LMNA | |
| SCHEMBL5712945 | 0.78 | ALDH1A1 (0.62) | TDP1ALDH1A1TSHRGPR35SMN1; SMN2 | |
| SCHEMBL28774866 | 0.78 | CYP3A4 (0.56) | TDP1ALDH1A1TSHRGPR35LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 251 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024101298-A1 | METHOD FOR PRODUCING MACROLIDE COMPOUND | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 2024-05-16 | — | — | WO | claimed |
| CN-110330500-B | Stereoselective synthesis method of 6 beta-hydroxy-7, 8-dihydro-morphine derivative | 宜昌人福药业有限责任公司 | 2021-11-23 | — | — | CN | claimed |
| CN-110305142-B | Stereoselective synthesis method of 6 beta-hydroxymorphine derivative | 宜昌人福药业有限责任公司 | 2021-11-16 | — | — | CN | claimed |
| CN-110330500-A | A kind of Stereoselective synthesizing process of 6 beta-hydroxy -7,8- dihydro-morphine derivatives | 宜昌人福药业有限责任公司 | 2019-10-15 | — | — | CN | claimed |
| EP-3205646-A2 | INTERMEDIATES FOR THE MANUFACTURE OF (R)-5-[2- (5,6-DIETHYLINDAN-2-YLAMINO)-1-HYDROXYETHYL]-8-HYDROXY-(1H)-QUINOLIN-2-ONE (INDACATEROL) | Laboratorios Lesvi, S.L. (ES) | 2017-08-16 | — | — | EP | claimed |
| EP-2978745-A1 | PROCESS FOR THE MANUFACTURE OF (R)-5-[2-(5,6-DIETHYLINDAN-2-YLAMINO)-1-HYDROXYETHYL]-8-HYDROXY-(1H)-QUINOLIN-2-ONE | Laboratorios Lesvi, S.L. (ES) | 2016-02-03 | — | — | EP | claimed |
| WO-2014154841-A1 | PROCESS FOR THE MANUFACTURE OF (R)-5-[2-(5,6-DIETHYLINDAN-2-YLAMINO)-1-HYDROXYETHYL]-8-HYDROXY-(1H)-QUINOLIN-2-ONE | LABORATORIOS LESVI, S.L. (ES) | 2014-10-02 | — | — | WO | claimed |
| CN-101723846-B | Novel 18F labeled p-nitro benzoyl amino acid derivatives, preparation method and application thereof in tumor imaging | UNIV BEIJING NORMAL | 2013-11-06 | — | — | CN | claimed |
| CN-101967149-A | New18F substituted nitro-labeled pyrazolo [1,5-a] pyrimidine compounds, their preparation and application | UNIV BEIJING NORMAL | 2011-02-09 | — | — | CN | claimed |
| CN-101723846-A | Novel 18F labeled p-nitro benzoyl amino acid derivatives, preparation method and application thereof in tumor imaging | UNIV BEIJING NORMAL | 2010-06-09 | — | — | CN | claimed |
| WO-2008072849-A1 | METHOD OF PREPARING DOCETAXEL AND INTERMEDIATES USED THEREIN | HANMI PHARM. CO., LTD. (KR) | 2008-06-19 | — | — | WO | claimed |
| US-6380197-B1 | FOR TREATING AND PREVENTING A PLETHORA OF DISEASES INCLUDING DIABETES | AVENTIS PHARMA S. A. (FR) | 2002-04-30 | — | — | US | claimed |
| EP-1001943-A1 | POLYHYDROXYALKYLPYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM | Aventis Pharma S.A. (FR) | 2000-05-24 | — | — | EP | claimed |
| WO-1999003843-A1 | POLYHYDROXYALKYLPYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM | RHONE-POULENC RORER S.A. (FR) | 1999-01-28 | — | — | WO | claimed |
| EP-0725787-A1 | ACTIVATED NUCLEOSIDE PHOSPHORAMIDITES AND METHODS FOR THE PREPARATION AND USE THEREOF | BECKMAN INSTRUMENTS, INC. (US) | 1996-08-14 | — | — | EP | claimed |
| WO-1996006853-A1 | ACTIVATED NUCLEOSIDE PHOSPHORAMIDITES AND METHODS FOR THE PREPARATION AND USE THEREOF | BECKMAN INSTRUMENTS, INC. (US) | 1996-03-07 | — | — | WO | claimed |
| US-5049681-A | Optically active allyl alcohol and process for producing leucotriene B.sub.4 | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1991-09-17 | — | — | US | claimed |
| EP-0259268-A1 | Process for the preparation of optically active beta-lactams | CIBA-GEIGY AG (CH) | 1988-03-09 | — | — | EP | claimed |
| EP-0092830-A2 | Cephalosporin derivatives, process for their preparation, pharmaceutical compositions containing them and their application | CIBA-GEIGY AG (CH) | 1983-11-02 | — | — | EP | claimed |
| US-4310459-A | Process for producing carbamoyl substituted penams and carbamoyl substituted cephams from penicillin sulfoxide esters | BRISTOL-MYERS COMPANY (US) | 1982-01-12 | — | — | US | claimed |