Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 4/20 | 0.63 |
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.47 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.47 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1795445 | 1.00 | AOC3 (0.63) | AOC3TSHRALDH1A1CNR2LMNA | |
| SCHEMBL1794281 | 0.85 | AOC3 (0.64) | AOC3TSHRALDH1A1CARM1PRMT6 | |
| SCHEMBL833414 | 0.85 | AOC3 (0.64) | AOC3TSHRALDH1A1CARM1PRMT6 | |
| Hydrochloric Acid SCHEMBL11779718 | 0.82 | AOC3 (0.61) | AOC3TSHRALDH1A1LMNACARM1 | |
| SCHEMBL9643574 | 0.82 | AOC3 (0.56) | AOC3TSHRALDH1A1CNR2CARM1 | |
| SCHEMBL11181580 | 0.79 | AOC3 (0.52) | AOC3TSHRALDH1A1CARM1PRMT6 | |
| SCHEMBL18884371 | 0.77 | AOC3 (1.00) | AOC3CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL2767287 | 0.77 | KCNH2 (0.50) | AOC3TSHRALDH1A1CNR2CARM1 | |
| SCHEMBL16257816 | 0.76 | AOC3 (0.54) | AOC3TSHRALDH1A1CARM1PRMT6 | |
| SCHEMBL1348975 | 0.76 | TSHR (0.54) | AOC3TSHRALDH1A1CNR2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115894884-A | Trifunctional organic catalyst, and preparation method and application thereof | 浙江大学 | 2023-04-04 | — | — | CN | claimed |
| EP-3064530-B1 | XYLYLENE DIAMINE COMPOSITION, AND METHOD FOR PRODUCING POLYAMIDE RESIN | MITSUBISHI GAS CHEMICAL CO (JP) | 2018-09-05 | — | — | EP | claimed |
| CN-105683253-B | The manufacture method of benzene dimethylamine composition and polyamide | 三菱瓦斯化学株式会社 | 2017-10-20 | — | — | CN | claimed |
| US-9637594-B2 | Xylylene diamine composition, and method for producing polyamide resin | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2017-05-02 | — | — | US | claimed |
| US-20160304671-A1 | XYLYLENE DIAMINE COMPOSITION, AND METHOD FOR PRODUCING POLYAMIDE RESIN | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2016-10-20 | — | — | US | claimed |
| EP-3064530-A1 | XYLYLENE DIAMINE COMPOSITION, AND METHOD FOR PRODUCING POLYAMIDE RESIN | Mitsubishi Gas Chemical Company, Inc. (JP) | 2016-09-07 | — | — | EP | claimed |
| CN-105683253-A | Xylylene diamine composition, and method for producing polyamide resin | 三菱瓦斯化学株式会社 | 2016-06-15 | — | — | CN | claimed |
| CN-115894884-B | Trifunctional organic catalyst and preparation method and application thereof | 浙江大学 | 2024-07-05 | — | — | CN | disclosed |
| US-20230203048-A1 | SPIROPYRROLIDINE DERIVED ANTIVIRAL AGENTS | ENANTA PHARMACEUTICALS, INC. | 2023-06-29 | — | — | US | disclosed |
| CN-115894884-A | Trifunctional organic catalyst, and preparation method and application thereof | 浙江大学 | 2023-04-04 | — | — | CN | disclosed |
| US-11564911-B2 | Small molecule dual-inhibitors of TRPV4 and TRPA1 for sanitizing and anesthetizing | DUKE UNIVERSITY (US) | 2023-01-31 | — | — | US | disclosed |
| CN-114651025-A | Curable composition, cured product, fiber-reinforced composite material, molded article, and method for producing same | DIC株式会社 | 2022-06-21 | — | — | CN | disclosed |
| US-11014896-B2 | TRPA1 and TRPV4 inhibitors and methods of using the same for organ-specific inflammation and itch | DUKE UNIVERSITY (US) | 2021-05-25 | — | — | US | disclosed |
| EP-1790639-A1 | COMPOUND CONTAINING BASIC GROUP AND USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-05-30 | — | — | EP | disclosed |
| CN-1515574-A | Substituted 7-acylamino-3-(methyldiazanediyl) methylcephalosporin and intermediate body with antibiotic action | 生物化学有限公司 | 2004-07-28 | — | — | CN | disclosed |
| CN-1117095-C | Substituted 7-acylamino-3- (methylhydrazono) methylcephalosporin with antibacterial action and intermediate | BIOCHEMIE CO LTD (AT) | 2003-08-06 | — | — | CN | disclosed |
| CN-1251591-A | Substituted 7-acylamino-3- (methylhydrazono) methylcephalosporin with antibacterial action and intermediate | BIOCHEMIE CO LTD (AT) | 2000-04-26 | — | — | CN | disclosed |
| US-4397965-A | HYDRAZINE DERIVATIVE BLOWING AGENT | UNIROYAL, INC. (US) | 1983-08-09 | — | — | US | disclosed |
| EP-0083173-A1 | Expandable and curable polyester composition and method for making same | UNIROYAL, INC. (US) | 1983-07-06 | — | — | EP | disclosed |
| US-4131685-A | ADRENERGIC BLOCKING AGENT, CARDIAC STIMULANT | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1978-12-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230203048-A1 | SPIROPYRROLIDINE DERIVED ANTIVIRAL AGENTS | ACE, ACE2, PKD1 | AOC3 4484/4885TSHR 3479/4885ALDH1A1 319/4885 |
| US-11564911-B2 | Small molecule dual-inhibitors of TRPV4 and TRPA1 for sanitizing and anesthetizing | TRPA1, TRPV4, TRPV1 | AOC3 2224/4885TSHR 3969/4885ALDH1A1 1975/4885 |
| US-11014896-B2 | TRPA1 and TRPV4 inhibitors and methods of using the same for organ-specific inflammation and itch | TRPA1, TRPV4, TRPV2 | AOC3 1417/4885TSHR 4260/4885ALDH1A1 2640/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.