SCHEMBL17969766

SCHEMBL17969766

CC1=C(C)/C(=C2/C(C)=C(C)C(=O)c3ccccc32)c2ccccc2C1=O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CDC25B P30305 9/20 0.58
▸ CDC25A P30304 7/20 0.58
▸ AURKA O14965 1/20 0.58
▸ AURKB Q96GD4 1/20 0.58
▸ S100A4 P26447 7/20 0.54
▸ MEN1 O00255 3/20 0.52
▸ KMT2A Q03164 3/20 0.52
▸ MAP2K7 O14733 4/20 0.50
▸ MAPT P10636 4/20 0.50
▸ MAOA P21397 3/20 0.50
▸ LMNA P02545 3/20 0.50
▸ BLM P54132 3/20 0.50
▸ SMN1; SMN2 Q16637 3/20 0.50
▸ RAB9A P51151 3/20 0.50
▸ PLIN1 O60240 2/20 0.50
▸ MAPK1 P28482 2/20 0.50
▸ PLIN5 Q00G26 2/20 0.50
▸ ABHD5 Q8WTS1 2/20 0.50
▸ KDM4E B2RXH2 2/20 0.50
▸ POLB P06746 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL571026 0.89 CDC25B (0.68) CDC25BCDC25AAURKAAURKBS100A4
SCHEMBL29941466 0.89 CDC25B (0.68) CDC25BCDC25AAURKAAURKBS100A4
Water SCHEMBL8664586 0.87 CDC25B (0.65) CDC25BCDC25AAURKAAURKBS100A4
SCHEMBL15491792 0.84 CDC25B (0.62) CDC25BCDC25AAURKAAURKBS100A4
SCHEMBL1556617 0.82 CDC25B (0.60) CDC25BCDC25AAURKAAURKBS100A4
SCHEMBL5138652 0.79 CDC25B (0.58) CDC25BCDC25AAURKAAURKBS100A4
SCHEMBL8586117 0.77 S100A4 (0.60) CDC25BCDC25AAURKAAURKBS100A4
SCHEMBL10503148 0.76 CDC25B (0.54) CDC25BCDC25AAURKAAURKBS100A4
SCHEMBL769933 0.75 MEN1 (0.80) CDC25BCDC25AS100A4MEN1KMT2A
SCHEMBL29402128 0.75 MEN1 (0.80) CDC25BCDC25AS100A4MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9760029-B2 Electrophotographic photosensitive member, image forming apparatus, and process cartridge KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2017-09-12 — — US disclosed
US-9760029-B2 Electrophotographic photosensitive member, image forming apparatus, and process cartridge KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2017-09-12 — — US disclosed
US-20160223923-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2016-08-04 — — US disclosed
US-20160223923-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2016-08-04 — — US disclosed
EP-3051352-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER AND METHOD FOR MANUFACTURING THE SAME, AND IMAGE FORMING APPARATUS Kyocera Document Solutions Inc. (JP) 2016-08-03 — — EP disclosed
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