SCHEMBL17969801

SCHEMBL17969801

CC1=C(C(=O)OCc2ccc(C)cc2)C(=O)c2ccccc2C1=O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 12/20 0.61
LMNA P02545 9/20 0.61
ALDH1A1 P00352 9/20 0.61
MEN1 O00255 7/20 0.61
KMT2A Q03164 7/20 0.61
HPGD P15428 6/20 0.61
NPSR1 Q6W5P4 6/20 0.61
SMN1; SMN2 Q16637 6/20 0.61
TDP1 Q9NUW8 5/20 0.61
ALOX12 P18054 4/20 0.61
HTT P42858 3/20 0.61
PKM P14618 3/20 0.61
STAT3 P40763 1/20 0.61
KCNH2 Q12809 1/20 0.61
MMP2 P08253 2/20 0.50
MMP12 P39900 2/20 0.50
MMP1 P03956 1/20 0.50
MMP9 P14780 1/20 0.50
KDM4E B2RXH2 7/20 0.49
HKDC1 Q2TB90 4/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17969774 0.91 ALDH1A1 (0.56) MAPTLMNAALDH1A1MEN1KMT2A
SCHEMBL17969808 0.87 NPC1 (0.50) MAPTLMNAALDH1A1MEN1KMT2A
SCHEMBL17969752 0.83 MAPT (0.44) MAPTLMNAALDH1A1MEN1KMT2A
SCHEMBL17969756 0.78 MAPT (0.49) MAPTLMNAALDH1A1MEN1KMT2A
SCHEMBL8285454 0.76 MAPT (1.00) MAPTLMNAALDH1A1MEN1KMT2A
SCHEMBL17969797 0.76 MAPT (0.45) MAPTLMNAALDH1A1MEN1KMT2A
SCHEMBL8340214 0.75 MAPT (0.56) MAPTLMNAALDH1A1MEN1KMT2A
SCHEMBL2354687 0.73 KMT2A (0.76) MAPTLMNAALDH1A1MEN1KMT2A
SCHEMBL445362 0.72 ALDH1A1 (0.56) MAPTLMNAALDH1A1MEN1KMT2A
SCHEMBL12761941 0.72 ALDH1A1 (0.51) MAPTLMNAALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9760029-B2 Electrophotographic photosensitive member, image forming apparatus, and process cartridge KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2017-09-12 US disclosed
US-9760029-B2 Electrophotographic photosensitive member, image forming apparatus, and process cartridge KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2017-09-12 US disclosed
US-20160223923-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2016-08-04 US disclosed
US-20160223923-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2016-08-04 US disclosed
EP-3051352-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER AND METHOD FOR MANUFACTURING THE SAME, AND IMAGE FORMING APPARATUS Kyocera Document Solutions Inc. (JP) 2016-08-03 EP disclosed