SCHEMBL445362

SCHEMBL445362

O=C(OCc1ccccc1)C1=C(c2ccccc2)C(=O)c2ccccc2C1=O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.56
LMNA P02545 4/20 0.56
SMN1; SMN2 Q16637 3/20 0.56
KMT2A Q03164 3/20 0.56
TDP1 Q9NUW8 3/20 0.56
HSP90AA1 P07900 2/20 0.56
MEN1 O00255 2/20 0.56
HKDC1 Q2TB90 2/20 0.56
NPSR1 Q6W5P4 2/20 0.56
L3MBTL1 Q9Y468 2/20 0.56
NPC1 O15118 2/20 0.56
MAPT P10636 2/20 0.56
RAB9A P51151 2/20 0.56
KDM4E B2RXH2 1/20 0.56
TP53 P04637 1/20 0.56
MAPK1 P28482 1/20 0.56
MPI P34949 1/20 0.56
HTT P42858 1/20 0.56
HSP90AB1 P08238 1/20 0.56
FGFR1 P11362 5/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8340214 0.97 MAPT (0.56) ALDH1A1LMNASMN1; SMN2KMT2ATDP1
SCHEMBL21470357 0.91 MAPT (0.57) ALDH1A1LMNASMN1; SMN2KMT2ATDP1
SCHEMBL21470361 0.91 ALDH1A1 (0.54) ALDH1A1LMNASMN1; SMN2KMT2ATDP1
SCHEMBL13986150 0.86 RAB9A (0.52) ALDH1A1LMNASMN1; SMN2KMT2ATDP1
SCHEMBL17969781 0.84 ALDH1A1 (0.78) ALDH1A1LMNASMN1; SMN2KMT2ATDP1
SCHEMBL15827661 0.82 NPSR1 (0.56) ALDH1A1LMNASMN1; SMN2KMT2ATDP1
SCHEMBL13679127 0.82 NPSR1 (0.56) ALDH1A1LMNASMN1; SMN2KMT2ATDP1
SCHEMBL17969774 0.81 ALDH1A1 (0.56) ALDH1A1LMNASMN1; SMN2KMT2ATDP1
SCHEMBL9658266 0.79 TDP1 (0.66) ALDH1A1LMNASMN1; SMN2KMT2ATDP1
SCHEMBL20707310 0.79 PPARG (0.44) ALDH1A1LMNASMN1; SMN2KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 321 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9285692-B2 Positively-charged single-layer electrophotographic photoreceptor and image forming apparatus KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2016-03-15 US claimed
US-6444385-B1 None US disclosed
US-20230340194-A1 RESIN, RESIN PRECURSOR COMPOSITION, COATING COMPOSITION, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, MOLDED ARTICLE, ELECTRONIC DEVICE, AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR PRODUCTION METHOD IDEMITSU KOSAN CO.,LTD. (JP) 2023-10-26 US disclosed
US-20230296995-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE, AND IMAGE FORMING DEVICE MITSUBISHI CHEMICAL CORPORATION (JP) 2023-09-21 US disclosed
US-20230296995-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE, AND IMAGE FORMING DEVICE MITSUBISHI CHEMICAL CORPORATION (JP) 2023-09-21 US disclosed
US-20230273535-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE, AND IMAGE FORMING DEVICE MITSUBISHI CHEMICAL CORPORATION (JP) 2023-08-31 US disclosed
US-20230273535-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE, AND IMAGE FORMING DEVICE MITSUBISHI CHEMICAL CORPORATION (JP) 2023-08-31 US disclosed
EP-3431524-B1 POLYCARBONATE RESIN, METHOD FOR PRODUCING POLYCARBONATE RESIN, COATING LIQUID, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND ELECTROPHOTOGRAPHY DEVICE IDEMITSU KOSAN CO (JP) 2023-06-07 EP disclosed
US-20230056801-A1 Electrophotographic Photoreceptor, Electrophotographic Photoreceptor Cartridge, and Image Forming Device MITSUBISHI CHEMICAL CORPORATION (JP) 2023-02-23 US disclosed
US-20220413404-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2022-12-29 US disclosed
US-RE39516-E1 Single-layer type electrophotosensitive material and image forming apparatus using the same KYOCERA MITA CORPORATION (JP) 2007-03-13 US disclosed
US-RE39516-E1 Single-layer type electrophotosensitive material and image forming apparatus using the same KYOCERA MITA CORPORATION (JP) 2007-03-13 US disclosed
US-20070023747-A1 Positive charging photoreceptor XEROX CORPORATION (US) 2007-02-01 US disclosed
US-20070023747-A1 Positive charging photoreceptor XEROX CORPORATION (US) 2007-02-01 US disclosed
EP-1093025-B1 Titanyl phthalocyanine crystal and production method of the same and electrophotosensitive material KYOCERA MITA CORP (JP) 2007-01-31 EP disclosed
US-7163771-B2 Imaging members XEROX CORPORATION (US) 2007-01-16 US disclosed
US-7163771-B2 Imaging members XEROX CORPORATION (US) 2007-01-16 US disclosed
US-6444385-B2 PREVENT PIGMENT AGGREGATION KYOCERA MITA CORPORATION (JP) 2002-09-03 US disclosed
US-20010038960-A1 Electrophotosensitive material and method of producing the same KYOCERA MITA CORPORATION (JP) 2001-11-08 US disclosed
EP-1146396-A2 Method of producing electrophotosensitive material and electrophotosensitive material produced by the method KYOCERA MITA CORPORATION (JP) 2001-10-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220413404-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS PCNA, RPA3, PCBP1 ALDH1A1 2516/4885LMNA 2349/4885SMN1; SMN2 4419/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.