Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.43 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17971057 | 0.90 | HPGD (0.44) | HPGDSMN1; SMN2L3MBTL1KMT2AMEN1 | |
| SCHEMBL6357661 | 0.74 | SGMS2 (0.52) | HPGDSMN1; SMN2L3MBTL1KMT2AMEN1 | |
| SCHEMBL2228229 | 0.73 | HPGD (0.67) | HPGDSMN1; SMN2ALDH1A1POLBNPC1 | |
| SCHEMBL1396290 | 0.73 | ALDH1A1 (0.57) | HPGDSMN1; SMN2L3MBTL1KMT2APTGER4 | |
| SCHEMBL17974510 | 0.72 | ALDH1A1 (0.58) | HPGDKMT2AMEN1ALDH1A1HCRTR1 | |
| SCHEMBL16039621 | 0.72 | LMNA (0.57) | HPGDSMN1; SMN2L3MBTL1KMT2APTGER4 | |
| SCHEMBL17530107 | 0.71 | TSHR (0.63) | HPGDSMN1; SMN2L3MBTL1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL18037169 | 0.71 | ALDH1A1 (0.55) | HPGDSMN1; SMN2L3MBTL1KMT2APTGER4 | |
| SCHEMBL21023149 | 0.71 | SGMS2 (0.54) | HPGDL3MBTL1KMT2AMEN1ALDH1A1 | |
| SCHEMBL6358805 | 0.71 | SGMS2 (0.61) | HPGDL3MBTL1PTGER1PTGDR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160221992-A1 | DENDRITIC COMPOUNDS INCLUDING A CHELATING, FLUOROCHROME OR RECOGNITION AGENT, COMPOSITIONS INCLUDING SAME AND USES THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS (FR) | 2016-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160221992-A1 | DENDRITIC COMPOUNDS INCLUDING A CHELATING, FLUOROCHROME OR RECOGNITION AGENT, COMPOSITIONS INCLUDING SAME AND USES THEREOF | MSR1, CD74, CD4 | HPGD 3144/4885SMN1; SMN2 4449/4885L3MBTL1 3264/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.