Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.52 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.52 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GBA1 | P04062 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.46 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6358805 | 0.88 | SGMS2 (0.61) | SGMS2PTGDR2KCNA5HPGDPTGER1 | |
| SCHEMBL2228229 | 0.81 | HPGD (0.67) | HPGDSMN1; SMN2MAPTLMNARAB9A | |
| SCHEMBL6362836 | 0.78 | PTGER1 (0.55) | SGMS2AKR1C3SMN1; SMN2PTGER1RAB9A | |
| SCHEMBL6358385 | 0.77 | SGMS2 (0.73) | SGMS2PTGDR2AKR1C3HPGDSMN1; SMN2 | |
| SCHEMBL13812667 | 0.76 | PTGS1 (0.56) | SGMS2AKR1C3PTGER1LMNAMEN1 | |
| SCHEMBL9668573 | 0.75 | HTR1A (0.56) | SGMS2HPGDSMN1; SMN2PTGER1MAPT | |
| SCHEMBL8677028 | 0.75 | NPC1 (0.67) | HPGDSMN1; SMN2PTGER1MAPTL3MBTL1 | |
| SCHEMBL17971068 | 0.74 | HPGD (0.50) | SGMS2PTGDR2KCNA5HPGDSMN1; SMN2 | |
| SCHEMBL8540588 | 0.74 | NQO2 (0.53) | SMN1; SMN2PTGER1LMNAHTR1ADRD2 | |
| SCHEMBL27428219 | 0.73 | GAA (0.50) | SGMS2HPGDPTGER1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050009812-A1 | Remedies for stress diseases comprising mitochondrial benzodiazepine receptor antagonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 2005-01-13 | — | — | US | claimed |
| EP-1438973-A1 | REMEDIES FOR STRESS DISEASES COMPRISING MITOCHONDRIAL BENZODIAZEPINE RECEPTOR ANTAGONISTS | ONO PHARMACEUTICAL CO., LTD. (JP) | 2004-07-21 | — | — | EP | claimed |
| US-6887360-B2 | Stable, reduced gloss electrocoat compositions and methods for using the same | PPG INDUSTRIES OHIO, INC. (US) | 2005-05-03 | — | — | US | disclosed |
| US-20050009812-A1 | Remedies for stress diseases comprising mitochondrial benzodiazepine receptor antagonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 2005-01-13 | — | — | US | disclosed |
| EP-1438973-A1 | REMEDIES FOR STRESS DISEASES COMPRISING MITOCHONDRIAL BENZODIAZEPINE RECEPTOR ANTAGONISTS | ONO PHARMACEUTICAL CO., LTD. (JP) | 2004-07-21 | — | — | EP | disclosed |
| EP-1434825-A1 | STABLE, REDUCED GLOSS ELECTROCOAT COMPOSITIONS AND METHODS FOR USING THE SAME | PPG Industries Ohio, Inc. (US) | 2004-07-07 | — | — | EP | disclosed |
| WO-2003031523-A1 | STABLE, REDUCED GLOSS ELECTROCOAT COMPOSITIONS AND METHODS FOR USING THE SAME | PPG INDUSTRIES OHIO, INC. (US) | 2003-04-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050009812-A1 | Remedies for stress diseases comprising mitochondrial benzodiazepine receptor antagonists | TFAM, CYP11B2, CYP11B1 | SGMS2 3588/4885PTGDR2 778/4885KCNA5 561/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.