Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | APP | P05067 | 2/20 | 0.53 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.45 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 3/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | SNCA | P37840 | 2/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17971223 | 0.94 | MAPT (0.50) | MAPTLMNASMN1; SMN2APPPTGDR2 | |
| SCHEMBL19156069 | 0.92 | MAPT (0.57) | MAPTLMNASMN1; SMN2APPPTGDR2 | |
| SCHEMBL17958327 | 0.91 | APP (0.53) | MAPTLMNASMN1; SMN2APPPTGDR2 | |
| SCHEMBL16596241 | 0.91 | APP (0.53) | MAPTLMNASMN1; SMN2APPPTGDR2 | |
| SCHEMBL17971216 | 0.89 | APP (0.66) | MAPTLMNASMN1; SMN2APPPTGDR2 | |
| SCHEMBL16596307 | 0.89 | APP (0.51) | MAPTLMNASMN1; SMN2APPPTGDR2 | |
| SCHEMBL19156093 | 0.87 | MAPT (0.55) | MAPTLMNASMN1; SMN2APPPTGDR2 | |
| SCHEMBL16596257 | 0.86 | ENPP2 (0.51) | MAPTLMNASMN1; SMN2APPPTGDR2 | |
| SCHEMBL17971218 | 0.85 | ENPP2 (0.49) | MAPTLMNASMN1; SMN2APPPTGDR2 | |
| SCHEMBL17971229 | 0.84 | APP (0.57) | MAPTLMNASMN1; SMN2APPPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9714240-B2 | Vinyl autotaxin inhibitor compounds | PHARMAKEA, INC. (US) | 2017-07-25 | — | — | US | disclosed |
| US-20160222000-A1 | VINYL AUTOTAXIN INHIBITOR COMPOUNDS | DF 2024 IP ACQUISITION, LLC | 2016-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160222000-A1 | VINYL AUTOTAXIN INHIBITOR COMPOUNDS | ENPP2, SERPINB1, SERPINB10 | MAPT 327/4885LMNA 1583/4885SMN1; SMN2 2623/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.