Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.35 |
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16380503 | 0.96 | CES2 (0.33) | CES2PLA2G4B | |
| SCHEMBL12392832 | 0.84 | TSHR (0.35) | — | |
| SCHEMBL12392828 | 0.82 | — | — | |
| SCHEMBL12392837 | 0.82 | ALDH1A1 (0.31) | — | |
| SCHEMBL12392843 | 0.79 | CHRM2 (0.41) | — | |
| SCHEMBL15961497 | 0.79 | CES2 (0.37) | CES2PLA2G4BHSD17B10 | |
| SCHEMBL15223132 | 0.78 | KMT2A (0.40) | CES2PLA2G4BHSD17B10 | |
| SCHEMBL17231636 | 0.74 | NAAA (0.34) | CES2HSD17B10 | |
| SCHEMBL13672689 | 0.74 | TSHR (0.31) | — | |
| SCHEMBL10014775 | 0.73 | CES2 (0.41) | CES2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9943609-B2 | Protein-polymer-drug conjugates | MERSANA THERAPEUTICS, INC. (US) | 2018-04-17 | — | — | US | disclosed |
| US-20160220696-A1 | PROTEIN-POLYMER-DRUG CONJUGATES | MERSANA THERAPEUTICS, INC. | 2016-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160220696-A1 | PROTEIN-POLYMER-DRUG CONJUGATES | PBRM1, PEBP1, STAMBP | CES2 3612/4885PLA2G4B 3098/4885HCAR2 1940/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.