Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 2/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | GABRP | O00591 | 1/20 | 0.30 |
| ▸ | GABRD | O14764 | 1/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.30 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.30 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10392510 | 0.82 | GABRP (0.42) | HRH3TSHRTDP1GABRPGABRD | |
| SCHEMBL20204090 | 0.81 | HRH1 (0.36) | HRH1HRH4HRH3CYP2A6CYP2C9 | |
| SCHEMBL27698233 | 0.80 | KCNH2 (0.47) | TDP1GABRPGABRDGABRA1IDO1 | |
| SCHEMBL96533 | 0.78 | GABRP (0.30) | GABRPGABRDGABRA1IDO1GABRB1 | |
| SCHEMBL12829587 | 0.78 | KCNH2 (0.50) | TDP1GABRPGABRDGABRA1IDO1 | |
| SCHEMBL17974339 | 0.78 | HRH1 (0.37) | HRH1HRH4HRH3CYP2A6AKT2 | |
| SCHEMBL830188 | 0.78 | NOS3 (0.33) | HRH3 | |
| SCHEMBL95675 | 0.77 | KCNH2 (0.31) | — | |
| Hydrochloric Acid SCHEMBL17960736 | 0.77 | HRH1 (0.36) | HRH1HRH4HRH3CYP2A6 | |
| SCHEMBL13771999 | 0.77 | AOC3 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160222023-A1 | NOVEL MONOTHIOL MUCOLYTIC AGENTS | PARION SCIENCES, INC. (US) | 2016-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160222023-A1 | NOVEL MONOTHIOL MUCOLYTIC AGENTS | MUC1, MAN2A1, HRH2 | HRH1 12/4885HRH4 52/4885HRH3 45/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.