SCHEMBL17974885

SCHEMBL17974885

CC1(C)c2cc(-c3ccccc3)ccc2N(c2ccc(-c3cccc4c3-c3ccccc3C43c4ccccc4-c4ccccc43)cc2)c2ccc(-c3ccccc3)cc21

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PDE6D O43924 1/20 0.36
PDK2 Q15119 9/20 0.35
PGR P06401 6/20 0.33
TYMS P04818 1/20 0.32
AR P10275 1/20 0.30
FAAH O00519 1/20 0.30
MGLL Q99685 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22183303 0.94 PDK2 (0.36) PDE6DPDK2PGRTYMSAR
SCHEMBL22183353 0.93 PDK2 (0.36) PDE6DPDK2PGRTYMS
SCHEMBL17816744 0.93 PDE6D (0.38) PDE6DPDK2PGRAR
SCHEMBL19001901 0.91 PDK2 (0.35) PDE6DPDK2PGRTYMS
SCHEMBL17197603 0.90 PDE6D (0.38) PDE6DPDK2PGRTYMS
SCHEMBL15290070 0.89 PDK2 (0.42) PDE6DPDK2PGRFAAHMGLL
SCHEMBL15183557 0.89 PDK2 (0.42) PDE6DPDK2PGRFAAHMGLL
SCHEMBL25495747 0.88 PDK2 (0.36) PDE6DPDK2PGRTYMSAR
SCHEMBL22183310 0.88 PDK2 (0.37) PDE6DPDK2PGR
SCHEMBL25496108 0.88 PDK2 (0.38) PDE6DPDK2PGRARFAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11737354-B2 Organic light emitting device having a carbazole-based compound formed between a cathode and a light emitting layer and a spirobifluorene-monoamine-based compound formed between an anode and a light emitting layer LG CHEM, LTD. (KR) 2023-08-22 US disclosed
US-11737354-B2 Organic light emitting device having a carbazole-based compound formed between a cathode and a light emitting layer and a spirobifluorene-monoamine-based compound formed between an anode and a light emitting layer LG CHEM, LTD. (KR) 2023-08-22 US disclosed
US-20200295264-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2020-09-17 US disclosed
US-10714692-B2 Organic light emitting device having a carbazole-based compound formed between cathode and light emitting layer and a spirobifluorene-monoamine based compound formed between anode and light emitting layer LG CHEM, LTD. (KR) 2020-07-14 US disclosed
US-20160225993-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2016-08-04 US disclosed
US-20160225993-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2016-08-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200295264-A1 ORGANIC LIGHT EMITTING DEVICE TPH1, DRD1, CYP1A1 PDE6D 1540/4885PDK2 917/4885PGR 1268/4885
US-10714692-B2 Organic light emitting device having a carbazole-based compound formed between cathode and light emitting layer and a spirobifluorene-monoamine based compound formed between anode and light emitting layer COMT, MAOB, MAOA PDE6D 363/4885PDK2 227/4885PGR 967/4885
US-11737354-B2 Organic light emitting device having a carbazole-based compound formed between a cathode and a light emitting layer and a spirobifluorene-monoamine-based compound formed between an anode and a light emitting layer DRD1, TPH1, DRD3 PDE6D 1130/4885PDK2 358/4885PGR 1439/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.