SCHEMBL19001901

SCHEMBL19001901

CC1(C)c2ccccc2N(c2ccccc2)c2ccc(-c3cccc4c3-c3ccccc3C43c4ccccc4-c4ccc(-c5ccccc5)cc43)cc21

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 6/20 0.35
PDE6D O43924 1/20 0.34
PGR P06401 3/20 0.33
TYMS P04818 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22183353 0.98 PDK2 (0.36) PDK2PDE6DPGRTYMS
SCHEMBL17816744 0.94 PDE6D (0.38) PDK2PDE6DPGR
SCHEMBL17974885 0.91 PDE6D (0.36) PDK2PDE6DPGRTYMS
SCHEMBL22183303 0.90 PDK2 (0.36) PDK2PDE6DPGRTYMS
SCHEMBL808393 0.90 PDK2 (0.39) PDK2PDE6DPGRALDH1A1
SCHEMBL15183560 0.90 PDK2 (0.40) PDK2PDE6DPGR
SCHEMBL15183561 0.90 PDK2 (0.40) PDK2PDE6DPGR
SCHEMBL808313 0.90 PGR (0.40) PDK2PGRALDH1A1
SCHEMBL10038900 0.90 PDK2 (0.42) PDK2PGRALDH1A1
SCHEMBL19001836 0.89 PDK2 (0.38) PDK2PDE6DPGRTYMS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3390365-B1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2021-04-14 EP disclosed
WO-2017102063-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2017-06-22 WO disclosed