SCHEMBL17816744

SCHEMBL17816744

CC1(C)c2ccccc2N(c2ccc(-c3ccccc3)cc2)c2ccc(-c3cccc4c3-c3ccccc3C43c4ccccc4-c4ccccc4-c4ccccc43)cc21

nearest known ligand 0.38

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PDE6D O43924 1/20 0.38
PGR P06401 4/20 0.32
PDK2 Q15119 3/20 0.32
AR P10275 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19001901 0.94 PDK2 (0.35) PDE6DPGRPDK2
SCHEMBL17974885 0.93 PDE6D (0.36) PDE6DPGRPDK2AR
SCHEMBL13827407 0.92 PDE6D (0.37) PDE6DPGRAR
SCHEMBL22183353 0.91 PDK2 (0.36) PDE6DPGRPDK2
SCHEMBL13827876 0.91 PDE6D (0.40) PDE6DPGRPDK2AR
SCHEMBL17197541 0.90 PDE6D (0.41) PDE6DPDK2
SCHEMBL17197585 0.89 PDE6D (0.39) PDE6DPGRPDK2AR
SCHEMBL17974884 0.88 PGR (0.35) PDE6DPGRPDK2
SCHEMBL22183303 0.88 PDK2 (0.36) PDE6DPGRPDK2AR
SCHEMBL17816797 0.87 PDK2 (0.36) PDE6DPGRPDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10573818-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2020-02-25 US disclosed
US-20170317283-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2017-11-02 US disclosed
US-20170317283-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2017-11-02 US disclosed
WO-2016087017-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2016-06-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170317283-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES PIEZO1, LEF1, EFNA1 PDE6D 1911/4885PGR 1736/4885PDK2 893/4885
US-10573818-B2 Materials for organic electroluminescent devices PIEZO1, LEF1, EFNA1 PDE6D 1911/4885PGR 1736/4885PDK2 893/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.