SCHEMBL179750

SCHEMBL179750

CN(C)c1cc2ccccc2c2nc3ccccc3nc12

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TOP2A P11388 6/20 0.45
NCF1 P14598 1/20 0.44
KDM1A O60341 1/20 0.42
ALDH1A1 P00352 3/20 0.41
KDM4E B2RXH2 2/20 0.41
POLB P06746 1/20 0.41
GAA P10253 1/20 0.41
MYC P01106 1/20 0.41
MAX P61244 1/20 0.41
ACP1 P24666 2/20 0.40
NQO2 P16083 1/20 0.39
HIF1A Q16665 1/20 0.39
CYP1B1 Q16678 1/20 0.39
HSD17B10 Q99714 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
MEN1 O00255 1/20 0.39
HCRTR1 O43613 1/20 0.39
LMNA P02545 1/20 0.39
MAPT P10636 1/20 0.39
THRB P10828 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3281012 0.78 CHEK1 (0.47) ALDH1A1KDM4EPOLBGAAACP1
SCHEMBL5344059 0.75 ALDH1A1 (0.48) ALDH1A1KDM4EGAAACP1HIF1A
SCHEMBL5332652 0.74 MYC (0.58) TOP2AKDM1AALDH1A1KDM4EPOLB
SCHEMBL483522 0.74 MYC (0.41) TOP2AALDH1A1KDM4EPOLBMYC
SCHEMBL13367603 0.71 NCF1 (0.54) NCF1ALDH1A1HIF1ACYP1B1HSD17B10
SCHEMBL29581869 0.70 MAPT (0.56) ALDH1A1KDM4EPOLBGAAMYC
SCHEMBL7912388 0.70 MAPT (0.56) ALDH1A1KDM4EPOLBGAAMYC
SCHEMBL732274 0.70 MAPT (0.56) ALDH1A1KDM4EPOLBGAAMYC
SCHEMBL9340104 0.70 GAA (0.52) NCF1ALDH1A1KDM4EGAANQO2
SCHEMBL20548494 0.69 CYP1A2 (0.39) KDM1AALDH1A1KDM4EGAAACP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 385 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12297221-B2 Functionalization and purification of molecules by reversible group exchange ILLUMINA, INC. (US) 2025-05-13 US disclosed
US-20240384262-A1 LINKING SEQUENCE READS USING PAIRED CODE TAGS ILLUMINA, INC. 2024-11-21 US disclosed
US-11993772-B2 Linking sequence reads using paired code tags ILLUMINA, INC. (US) 2024-05-28 US disclosed
US-20230406874-A1 FUNCTIONALIZATION AND PURIFICATION OF MOLECULES BY REVERSIBLE GROUP EXCHANGE ILLUMINA, INC. 2023-12-21 US disclosed
US-11760772-B2 Functionalization and purification of molecules by reversible group exchange ILLUMINA, INC. (US) 2023-09-19 US disclosed
US-20210277043-A1 FUNCTIONALIZATION AND PURIFICATION OF MOLECULES BY REVERSIBLE GROUP EXCHANGE ILLUMINA, INC. (US) 2021-09-09 US disclosed
US-11021504-B2 Functionalization and purification of molecules by reversible group exchange ILLUMINA, INC. (US) 2021-06-01 US disclosed
US-11008567-B2 Oligonucleotide replacement for di-tagged and directional libraries ILLUMINA, INC. (US) 2021-05-18 US disclosed
EP-3722423-A1 FUNCTIONALIZATION AND PURIFICATION OF MOLECULES BY REVERSIBLE GROUP EXCHANGE Illumina, Inc. (US) 2020-10-14 EP disclosed
EP-2739732-B1 FUNCTIONALIZATION AND PURIFICATION OF MOLECULES BY REVERSIBLE GROUP EXCHANGE ILLUMINA INC (US) 2020-04-22 EP disclosed
US-4281061-A DETECTABLE SIGNAL FROM FLUORESCENT DYE OR LABELED ENZYME SYVA COMPANY (US) 1981-07-28 US disclosed
US-4275149-A IMMUNOASSAY SYVA COMPANY (US) 1981-06-23 US disclosed
US-4272506-A BINDING A LABELED MEMBER OF A SPECIFIC BINDING PAIR TO A MERCAPTO-ACTIVATED SUPPORT THROUGH CLEAVABLE DISULFIDE LINKAGES; IMMUNOASSAY; ACCURACY SYVA COMPANY (US) 1981-06-09 US disclosed
US-4256834-A REPRESSING THE SIGNALS PRODUCED BY UNBOUND LABELS; SENSITIVITY SYVA COMPANY (US) 1981-03-17 US disclosed
EP-0022768-A1 MACROMOLECULAR ENVIRONMENT CONTROL IN SPECIFIC RECEPTOR ASSAYS. SYVA CO (US) 1981-01-28 EP disclosed
EP-0017908-A1 A method for determining the presence in a sample of an analyte and a kit for use in this method SYVA COMPANY (US) 1980-10-29 EP disclosed
EP-0015695-A1 Support-ligand analog-fluorescer conjugate and serum assay method involving such conjugate SYVA COMPANY (US) 1980-09-17 EP disclosed
EP-0022768-A4 MACROMOLECULAR ENVIRONMENT CONTROL IN SPECIFIC RECEPTOR ASSAYS. SYVA CO (US) 1980-08-18 EP disclosed
US-4193983-A Labeled liposome particle compositions and immunoassays therewith SYVA COMPANY (US) 1980-03-18 US disclosed
WO-1979000882-A1 MACROMOLECULAR ENVIRONMENT CONTROL IN SPECIFIC RECEPTOR ASSAYS SYVA CO (US) 1979-11-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230406874-A1 FUNCTIONALIZATION AND PURIFICATION OF MOLECULES BY REVERSIBLE GROUP EXCHANGE PHAX, ALKBH1, JMJD6 TOP2A 1501/4885NCF1 1722/4885KDM1A 1067/4885
US-11021504-B2 Functionalization and purification of molecules by reversible group exchange PHAX, ALKBH1, JMJD6 TOP2A 1501/4885NCF1 1722/4885KDM1A 1067/4885
US-20210277043-A1 FUNCTIONALIZATION AND PURIFICATION OF MOLECULES BY REVERSIBLE GROUP EXCHANGE PHAX, ALKBH1, JMJD6 TOP2A 1501/4885NCF1 1722/4885KDM1A 1067/4885
US-12297221-B2 Functionalization and purification of molecules by reversible group exchange PHAX, ALKBH1, JMJD6 TOP2A 1501/4885NCF1 1722/4885KDM1A 1067/4885
US-11760772-B2 Functionalization and purification of molecules by reversible group exchange PHAX, ALKBH1, JMJD6 TOP2A 1501/4885NCF1 1722/4885KDM1A 1067/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.