Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17960724 | 0.82 | PTGES (0.36) | KDM4EMAPTKMT2AMEN1HTT | |
| SCHEMBL17975240 | 0.79 | SMN1; SMN2 (0.37) | KDM4EMAPTKMT2AMEN1HTT | |
| SCHEMBL17975243 | 0.77 | KMT2A (0.44) | KDM4EMAPTKMT2AHTTSMN1; SMN2 | |
| SCHEMBL17975242 | 0.75 | MGAM (0.41) | KDM4EMAPTKMT2AMEN1HTT | |
| SCHEMBL17975244 | 0.74 | PTGES (0.39) | KDM4EMAPTKMT2AMEN1HTT | |
| SCHEMBL17960575 | 0.64 | PTGES (0.35) | KDM4EMAPTKMT2AMEN1HTT | |
| SCHEMBL17975239 | 0.64 | SMN1; SMN2 (0.60) | KDM4EMAPTKMT2AMEN1HTT | |
| SCHEMBL2795120 | 0.62 | BRD4 (0.39) | KDM4EMAPTKMT2AMEN1HTT | |
| SCHEMBL15294677 | 0.61 | BRD4 (0.34) | KDM4EMAPTKMT2AMEN1HTT | |
| SCHEMBL19911450 | 0.60 | GAA (0.62) | KDM4ESMN1; SMN2ALDH1A1HPGDGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160222042-A1 | NOVEL PHOSPHINES, SYNTHESIS THEREOF AND THEIR USE IN CATALYSIS | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2016-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160222042-A1 | NOVEL PHOSPHINES, SYNTHESIS THEREOF AND THEIR USE IN CATALYSIS | PHOSPHO1, PPIP5K2, PDXK | KDM4E 2616/4885MAPT 4670/4885KMT2A 1445/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.