Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17960575 | 0.84 | PTGES (0.35) | PTGESKDM4EALDH1A1GAAGLA | |
| SCHEMBL17975233 | 0.82 | KDM4E (0.38) | KDM4EALDH1A1GAAGLAHPGD | |
| SCHEMBL16586347 | 0.80 | LMNA (0.48) | ALDH1A1SMN1; SMN2LMNAMAPTHTT | |
| SCHEMBL16596912 | 0.80 | PTGES (0.42) | PTGESKDM4EALDH1A1GAAGLA | |
| SCHEMBL17960722 | 0.79 | MGAM (0.37) | PTGESKDM4EALDH1A1GAAHPGD | |
| SCHEMBL16596945 | 0.79 | PTGES (0.41) | PTGESKDM4EALDH1A1GAAGLA | |
| SCHEMBL16596881 | 0.78 | PTGES (0.37) | PTGESKDM4EALDH1A1GAAGLA | |
| SCHEMBL17960699 | 0.78 | LMNA (0.36) | PTGESKDM4EALDH1A1GAAHPGD | |
| SCHEMBL17960678 | 0.76 | PTGES (0.33) | PTGESKDM4EALDH1A1GLAHPGD | |
| SCHEMBL17975240 | 0.68 | SMN1; SMN2 (0.37) | PTGESKDM4EALDH1A1GAAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10093692-B2 | Phosphines, synthesis thereof and their use in catalysis | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2018-10-09 | — | — | US | claimed |
| US-20160222042-A1 | NOVEL PHOSPHINES, SYNTHESIS THEREOF AND THEIR USE IN CATALYSIS | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2016-08-04 | — | — | US | claimed |
| US-10093692-B2 | Phosphines, synthesis thereof and their use in catalysis | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2018-10-09 | — | — | US | disclosed |
| US-20160222042-A1 | NOVEL PHOSPHINES, SYNTHESIS THEREOF AND THEIR USE IN CATALYSIS | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2016-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160222042-A1 | NOVEL PHOSPHINES, SYNTHESIS THEREOF AND THEIR USE IN CATALYSIS | PHOSPHO1, PPIP5K2, PDXK | PTGES 2053/4885KDM4E 2616/4885ALDH1A1 3824/4885 |
| US-10093692-B2 | Phosphines, synthesis thereof and their use in catalysis | PPIP5K2, PHOSPHO1, ITPA | PTGES 1962/4885KDM4E 2704/4885ALDH1A1 3683/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.