Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dipyridyl SCHEMBL6466948 | 0.74 | — | — | |
| SCHEMBL30116309 | 0.70 | ACHE (0.33) | ACHE | |
| SCHEMBL1681880 | 0.68 | ACHE (0.36) | ACHE | |
| SCHEMBL16415848 | 0.68 | ALDH1A1 (0.36) | ACHE | |
| SCHEMBL28185832 | 0.67 | — | — | |
| SCHEMBL22129788 | 0.65 | TSHR (0.32) | TSHR | |
| Toluene SCHEMBL28233532 | 0.64 | ACHE (0.73) | ACHETSHR | |
| Toluene SCHEMBL16742093 | 0.64 | ACHE (0.73) | ACHETSHR | |
| Quinoline SCHEMBL6336123 | 0.63 | CYP2A6 (0.32) | — | |
| SCHEMBL3351116 | 0.63 | ACHE (0.32) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9844773-B2 | Picolinamide-cinchona organocatalysts and derivatives | UNIVERSIDADE DE EVORA (PT) | 2017-12-19 | — | — | US | disclosed |
| US-20160236184-A1 | NOVEL PICOLINAMIDE-CINCHONA ORGANOCATALYSTS AND DERIVATIVES | UNIVERSIDADE DE EVORA (PT) | 2016-08-18 | — | — | US | disclosed |
| EP-3055062-A1 | NOVEL PICOLINAMIDE-CINCHONA ORGANOCATALYSTS AND DERIVATIVES | Universidade de Évora (PT) | 2016-08-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160236184-A1 | NOVEL PICOLINAMIDE-CINCHONA ORGANOCATALYSTS AND DERIVATIVES | KPNA2, MCM3, KPNA3 | ACHE 1577/4885TSHR 4653/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.