Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.43 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1799375 | 0.90 | ALDH1A1 (0.58) | ALDH1A1L3MBTL1KDM4ENPSR1MEN1 | |
| Hydrochloric Acid SCHEMBL1800403 | 0.89 | ALDH1A1 (0.57) | ALDH1A1L3MBTL1KDM4ENPSR1MEN1 | |
| SCHEMBL1798978 | 0.85 | SERPINE1 (0.53) | ALDH1A1L3MBTL1KDM4EMEN1KMT2A | |
| SCHEMBL1796237 | 0.84 | ALDH1A1 (0.54) | ALDH1A1L3MBTL1KDM4ENPSR1MEN1 | |
| SCHEMBL1796902 | 0.81 | TP53 (0.65) | ALDH1A1L3MBTL1KDM4ENPSR1MEN1 | |
| SCHEMBL1800967 | 0.81 | CRHBP (0.46) | ALDH1A1L3MBTL1KDM4ENPSR1MEN1 | |
| SCHEMBL1796719 | 0.80 | SERPINE1 (0.63) | ALDH1A1L3MBTL1KDM4ENPSR1 | |
| SCHEMBL420909 | 0.80 | NPSR1 (0.56) | ALDH1A1KDM4ENPSR1MEN1KMT2A | |
| SCHEMBL418724 | 0.77 | ALDH1A1 (0.52) | ALDH1A1L3MBTL1KDM4ENPSR1MEN1 | |
| SCHEMBL1796300 | 0.75 | ALDH1A1 (0.48) | ALDH1A1KDM4EMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7951806-B2 | Plasminogen activator inhibitor-1 inhibitor | RENASCIENCE CO., LTD. (JP) | 2011-05-31 | — | — | US | disclosed |
| US-20090124620-A1 | PLASMINOGEN ACTIVATOR INHIBITOR-1 INHIBITOR | RENASCIENCE CO., LTD. (JP) | 2009-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090124620-A1 | PLASMINOGEN ACTIVATOR INHIBITOR-1 INHIBITOR | SERPINE1, SERPINC1, SERPINB1 | ALDH1A1 800/4885L3MBTL1 2672/4885KDM4E 4309/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.