Methacrylic Acid

Methacrylic Acid

SCHEMBL1798494

C=C(C)C(=O)O.C=CC(=O)OC(C)(C)C

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.35
TSHR P16473 7/20 0.32
TP53 P04637 4/20 0.31
HIF1A Q16665 3/20 0.31
CYP3A4 P08684 2/20 0.31
MAPK1 P28482 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
HPGD P15428 1/20 0.31
LMNA P02545 1/20 0.31
DGAT1 O75907 1/20 0.30
HSD17B10 Q99714 1/20 0.30
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL28208586 0.96 ALDH1A1 (0.32) ALDH1A1TSHR
Methacrylic Acid SCHEMBL27491190 0.96 LMNA (0.39) ALDH1A1TSHRLMNAHSD17B10
Methacrylic Acid SCHEMBL27682855 0.93 ALDH1A1 (0.34) ALDH1A1DGAT1
Methacrylic Acid SCHEMBL27682859 0.93 TSHR (0.38) ALDH1A1TSHRTP53HIF1ACYP3A4
Methacrylic Acid SCHEMBL27682861 0.89 ALDH1A1 (0.50) ALDH1A1TSHRDGAT1
SCHEMBL4610941 0.89 ALDH1A1 (0.39) ALDH1A1TSHRTP53HIF1ACYP3A4
Acetic Acid SCHEMBL28197409 0.89 ALDH1A1 (0.39) ALDH1A1TSHRTP53HIF1ACYP3A4
Hydrogen Peroxide SCHEMBL27482921 0.89 LMNA (0.38) ALDH1A1TSHRTP53HIF1ACYP3A4
Acrylic Acid Ethyl Ester SCHEMBL564981 0.88 TSHR (0.40) ALDH1A1TSHRTP53HIF1ACYP3A4
SCHEMBL17728154 0.87 TSHR (0.46) ALDH1A1TSHRTP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4431536-A1 AQUEOUS CATIONIC POLYMER EMULSION AND AQUEOUS CATIONIC POLYMER EMULSION PREPARATION METHOD CHT Turkey Kimya Sanayi ve Ticaret A.S. (TR) 2024-09-18 EP disclosed
CN-107920985-A Improved nano particle delivery system 塞拉特药物股份有限公司 2018-04-17 CN disclosed
US-7951888-B2 Block copolymer, composition comprising it and cosmetic treatment process L'OREAL S.A. (FR) 2011-05-31 US disclosed
CN-1997680-B Sequenced copolymer ARKEMA FRANCE 2011-01-12 CN disclosed
CN-101707914-A Resin composition TEIJIN LTD 2010-05-12 CN disclosed
US-20100055064-A1 BLOCK COPOLYMER, COMPOSITION COMPRISING IT AND COSMETIC TREATMENT PROCESS L'OREAL S.A. 2010-03-04 US disclosed
US-7632905-B2 Block copolymer, composition comprising it and cosmetic treatment process L'OREAL S.A. (FR) 2009-12-15 US disclosed
CN-101008782-A Coating composition for photoresist ROHM & HAAS ELECT MAT (US) 2007-08-01 CN disclosed
CN-1997680-A Sequenced copolymer ARKEMA FRANCE (FR) 2007-07-11 CN disclosed
US-20060030685-A1 Block copolymer, composition comprising it and cosmetic treatment process ARKEMA FRANCE (FR) 2006-02-09 US disclosed
US-20010036979-A1 Coloring composition, ink-jet ink and ink-jet recording method FUJI PHOTO FILM CO., LTD. (JP) 2001-11-01 US disclosed
US-5275847-A Polymerizing an acrylic ester with a monomer containing hydroxyl groups; further polymerization with a monomer containing carboxyl groups; top coating BASF LACKE+FARBEN AKTIENGESELLSCHAFT (DE) 1994-01-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100055064-A1 BLOCK COPOLYMER, COMPOSITION COMPRISING IT AND COSMETIC TREATMENT PROCESS KRT18, DSG1, TPRKB ALDH1A1 3163/4885TSHR 3376/4885TP53 267/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.