Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | KDM1A | O60341 | 2/20 | 0.41 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.41 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | ESRRA | P11474 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
| ▸ | HPGDS | O60760 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2094284 | 0.86 | ALDH1A1 (0.63) | ARALDH1A1USP2KDM4EKDM1A | |
| SCHEMBL21880260 | 0.86 | ALDH1A1 (0.40) | ARALDH1A1USP2KDM4EMAPT | |
| SCHEMBL1797171 | 0.85 | AR (0.49) | ARALDH1A1USP2KDM4EIMPDH2 | |
| SCHEMBL2793117 | 0.85 | ALDH1A1 (0.58) | ARALDH1A1USP2KDM4EIMPDH2 | |
| SCHEMBL30150359 | 0.85 | ALDH1A1 (0.58) | ARALDH1A1USP2KDM4EIMPDH2 | |
| SCHEMBL16951586 | 0.81 | AR (0.49) | ARALDH1A1USP2KDM4EKDM1A | |
| SCHEMBL509522 | 0.78 | AR (0.66) | ARALDH1A1USP2KDM4EKDM1A | |
| SCHEMBL29490258 | 0.78 | AR (0.66) | ARALDH1A1USP2KDM4EKDM1A | |
| SCHEMBL4669307 | 0.77 | ALDH1A1 (0.53) | ARALDH1A1USP2KDM4EIMPDH2 | |
| SCHEMBL11616908 | 0.76 | KDM1A (0.56) | ARALDH1A1USP2KDM4EKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7951827-B2 | Synthesis and antiprotozoal activity of dicationic 3,5-diphenylisoxazoles | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2011-05-31 | — | — | US | disclosed |
| US-20060264487-A1 | Synthesis and antiprotozoal activity of dicationic 3,5-diphenylisoxazoles | TIDWELL RICHARD R | 2006-11-23 | — | — | US | disclosed |
| EP-1719767-A1 | Synthesis and antiprotozoal activity of dicationic 3,5-diphenylisoxazoles | The University of North Carolina at Chapel Hill (US) | 2006-11-08 | — | — | EP | disclosed |
| US-6355490-B1 | CODING INDIVIDUAL MEMBERS OF LIBRARY; COVALENTLY BONDING NITRILE TO SOLID SUPPORT; DETECTION BY INFRARED OR RAMAN SPECTROSCOPY | ABBOTT LABORATORIES | 2002-03-12 | — | — | US | disclosed |
| US-6274385-B1 | COVALENTLY ATTACHING TO EACH SOLID SUPPORT AT LEAST ONE ACETYLENE CODING IDENTIFIER DETECTABLE BY INFRARED OR RAMAN SPECTROSCOPY TO CODE INDIVIDUAL MEMBERS OF A COMBINATORIAL CHEMICAL LIBRARY | ABBOTT LABORATORIES | 2001-08-14 | — | — | US | disclosed |
| EP-0879219-B1 | ATTACHED TAGS FOR USE IN COMBINATORIAL CHEMISTRY SYNTHESIS | ABBOTT LAB (US) | 2000-03-01 | — | — | EP | disclosed |
| EP-0879219-A1 | ATTACHED TAGS FOR USE IN COMBINATORIAL CHEMISTRY SYNTHESIS | Abbott Laboratories (US) | 1998-11-25 | — | — | EP | disclosed |
| WO-1998011036-A9 | ATTACHED TAGS FOR USE IN COMBINATORIAL CHEMISTRY SYNTHESIS | — | 1998-07-09 | — | — | WO | disclosed |
| WO-1998011036-A1 | ATTACHED TAGS FOR USE IN COMBINATORIAL CHEMISTRY SYNTHESIS | ABBOTT LABORATORIES (US) | 1998-03-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060264487-A1 | Synthesis and antiprotozoal activity of dicationic 3,5-diphenylisoxazoles | PFAS, DHPS, DDO | AR 4850/4885ALDH1A1 3221/4885USP2 4114/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.