Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17992004 | 0.88 | LMNA (0.54) | LMNARAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL17991993 | 0.87 | LMNA (0.45) | LMNARAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL17991985 | 0.87 | LMNA (0.45) | LMNARAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL17988686 | 0.87 | MAPT (0.50) | LMNARAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL14699614 | 0.87 | MAPT (0.50) | LMNARAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL17992015 | 0.83 | LMNA (0.42) | LMNARAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL17991987 | 0.81 | MAPT (0.43) | LMNARAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL17988721 | 0.78 | ALDH1A1 (0.39) | MAPTALDH1A1CYP1A2MEN1KMT2A | |
| SCHEMBL17988693 | 0.77 | PTGS2 (0.44) | LMNARAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL17991983 | 0.76 | STS (0.53) | LMNARAB9ANPC1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9409859-B2 | Substituted diphenyl derivatives | CREATIVE THERAPEUTICS GMBH (DE) | 2016-08-09 | — | — | US | disclosed |