Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17988693 | 0.95 | PTGS2 (0.44) | MAPTALDH1A1KDM4EHPGDNPC1 | |
| SCHEMBL17988694 | 0.85 | LMNA (0.42) | MAPTALDH1A1KDM4EHPGDNPC1 | |
| SCHEMBL17988686 | 0.83 | MAPT (0.50) | MAPTALDH1A1KDM4EHPGDNPC1 | |
| SCHEMBL14699614 | 0.83 | MAPT (0.50) | MAPTALDH1A1KDM4EHPGDNPC1 | |
| SCHEMBL17991992 | 0.81 | LMNA (0.49) | MAPTALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL17992004 | 0.79 | LMNA (0.54) | MAPTALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL15399023 | 0.78 | ESR1 (0.59) | MAPTALDH1A1KDM4EHPGDNPC1 | |
| SCHEMBL14506354 | 0.78 | MAPT (0.46) | MAPTALDH1A1KDM4EHPGDNPC1 | |
| SCHEMBL17991993 | 0.78 | LMNA (0.45) | MAPTALDH1A1KDM4EHPGDNPC1 | |
| SCHEMBL17991985 | 0.78 | LMNA (0.45) | MAPTALDH1A1KDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9409859-B2 | Substituted diphenyl derivatives | CREATIVE THERAPEUTICS GMBH (DE) | 2016-08-09 | — | — | US | disclosed |