SCHEMBL17990740

SCHEMBL17990740

c1ccc(-c2ccc(-c3ccc(-n4c5ccccc5c5c6c(ccc7oc8ccccc8c76)ccc54)nc3)c(-c3ccccc3)c2)cc1

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 1/20 0.33
PLA2G4A P47712 1/20 0.33
PGR P06401 1/20 0.31
TBK1 Q9UHD2 1/20 0.30
CDC14B O60729 1/20 0.30
CDC14A Q9UNH5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17990652 0.86 PGR (0.34) PLA2G2APLA2G4APGRCDC14BCDC14A
SCHEMBL17990961 0.82 PTPN1 (0.30)
SCHEMBL17246175 0.82 ALDH1A1 (0.32) PLA2G2APLA2G4A
SCHEMBL22514199 0.81
SCHEMBL17989700 0.79 MAP4K4 (0.30)
SCHEMBL14979442 0.78 CHEK2 (0.35) PLA2G2APLA2G4A
SCHEMBL17246186 0.78 ALOX5 (0.44) CDC14BCDC14A
SCHEMBL22514698 0.78 PLA2G2A (0.31) PLA2G2APLA2G4A
SCHEMBL22514619 0.78 MAPT (0.30) PLA2G2APLA2G4A
SCHEMBL12455091 0.76 PLA2G2A (0.42) PLA2G2APLA2G4APGRTBK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160225992-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-08-04 US disclosed
US-20160225992-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-08-04 US disclosed