SCHEMBL17992602

SCHEMBL17992602

CN[C@H](C(=O)N[C@H](C(=O)N(C)[C@H](/C=C(\C)C(=O)O)C(C)C)C(C)(C)C)C1CCCN(C(C)C)C1

nearest known ligand 0.61

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TUBB1 Q9H4B7 2/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22692374 1.00 TUBB1 (0.61) TUBB1
SCHEMBL57608 0.88 TUBB1 (0.74) TUBB1
SCHEMBL23394062 0.84 TUBB1 (0.41) TUBB1
SCHEMBL12202654 0.79 TUBB1 (0.60) TUBB1
SCHEMBL88548 0.77 TUBB1 (0.74) TUBB1
SCHEMBL13660108 0.77 TUBB1 (0.74) TUBB1
SCHEMBL58085 0.77 TUBB1 (0.74) TUBB1
SCHEMBL15434851 0.76 TUBB1 (0.67) TUBB1
SCHEMBL20732343 0.76 TUBB1 (1.00) TUBB1
SCHEMBL22308460 0.76 TUBB1 (1.00) TUBB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240238431-A1 Bispecific Antibody-Drug Conjugate BEIJING XUANZHU COMBIO CO., LTD. (CN) 2024-07-18 US disclosed
US-20240238431-A1 Bispecific Antibody-Drug Conjugate BEIJING XUANZHU COMBIO CO., LTD. (CN) 2024-07-18 US disclosed
EP-3892305-A1 HEMIASTERLIN DERIVATIVES FOR CONJUGATION AND THERAPY Sutro Biopharma, Inc. (US) 2021-10-13 EP disclosed
US-20160257709-A1 HEMIASTERLIN DERIVATIVES FOR CONJUGATION AND THERAPY SUTRO BIOPHARMA, INC. 2016-09-08 US disclosed
US-20160257709-A1 HEMIASTERLIN DERIVATIVES FOR CONJUGATION AND THERAPY SUTRO BIOPHARMA, INC. 2016-09-08 US disclosed
WO-2016123582-A1 HEMIASTERLIN DERIVATIVES FOR CONJUGATION AND THERAPY SUTRO BIOPHARMA, INC. (US) 2016-08-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240238431-A1 Bispecific Antibody-Drug Conjugate BSG, DSG1, HASPIN TUBB1 259/4885
US-20160257709-A1 HEMIASTERLIN DERIVATIVES FOR CONJUGATION AND THERAPY CYP17A1, HSD17B7, SHBG TUBB1 176/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.