Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT1 | P30419 | 6/20 | 0.41 |
| ▸ | NMT2 | O60551 | 5/20 | 0.41 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.37 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.35 |
| ▸ | CPB2 | Q96IY4 | 3/20 | 0.34 |
| ▸ | TLR2 | O60603 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.33 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.33 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17193584 | 0.91 | SIRT6 (0.40) | NMT1NMT2SIRT6SIRT1FOLH1 | |
| SCHEMBL24095650 | 0.88 | SIRT6 (0.41) | NMT1NMT2SIRT6SIRT1FOLH1 | |
| SCHEMBL16556724 | 0.86 | NMT2 (0.39) | NMT1NMT2SIRT6SIRT1FOLH1 | |
| SCHEMBL20729832 | 0.81 | CAPN1 (0.39) | NMT1NMT2SIRT6SIRT1FOLH1 | |
| SCHEMBL26334930 | 0.81 | CAPN1 (0.39) | NMT1NMT2SIRT6SIRT1FOLH1 | |
| SCHEMBL25519403 | 0.80 | CTSK (0.43) | NMT1NMT2SIRT6SIRT1CPB2 | |
| SCHEMBL15886963 | 0.79 | NMT2 (0.37) | NMT1NMT2SIRT6SIRT1CPB2 | |
| SCHEMBL12072835 | 0.77 | ECE1 (0.35) | — | |
| SCHEMBL13668922 | 0.76 | SIRT6 (0.46) | NMT1NMT2SIRT6SIRT1FOLH1 | |
| SCHEMBL13798774 | 0.76 | SIRT6 (0.46) | NMT1NMT2SIRT6SIRT1FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2571893-B1 | NOVEL CYCLODECAPEPTIDE COMPOUNDS FOR USE AS DRUGS | Commissariat à l'énergie atomique et aux énergies alternatives (FR) | 2016-08-10 | — | — | EP | disclosed |