Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 3/20 | 0.35 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16168241 | 0.80 | MME (0.39) | — | |
| SCHEMBL15866437 | 0.78 | PAX8 (0.35) | PDCD1LG2CD274PAX8 | |
| SCHEMBL17993335 | 0.77 | NMT1 (0.41) | — | |
| SCHEMBL16024777 | 0.77 | TASP1 (0.40) | ECE1 | |
| SCHEMBL16168238 | 0.75 | CASP1 (0.40) | — | |
| SCHEMBL25556572 | 0.73 | ECE1 (0.33) | ECE1PAX8 | |
| SCHEMBL8229032 | 0.73 | ECE1 (0.40) | ECE1PDCD1LG2CD274 | |
| SCHEMBL25556364 | 0.73 | ECE1 (0.40) | ECE1PDCD1LG2CD274 | |
| SCHEMBL24115245 | 0.73 | — | — | |
| SCHEMBL12900692 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011161699-A2 | IMMUNOSUPPRESSION MODULATING COMPOUNDS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2011-12-29 | — | — | WO | disclosed |