Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | PPARG | P37231 | 1/20 | 0.55 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.55 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.52 |
| ▸ | LMNA | P02545 | 7/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | PTPRC | P08575 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1800214 | 0.93 | RAB9A (0.56) | RAB9APOLBPPARGNCOA2NCOA1 | |
| SCHEMBL1796259 | 0.88 | RAB9A (0.52) | RAB9APOLBALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL1800530 | 0.88 | POLB (0.52) | RAB9APOLBPPARGNCOA2NCOA1 | |
| SCHEMBL1796981 | 0.87 | RAB9A (0.51) | RAB9APOLBALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL1799695 | 0.87 | RAB9A (0.51) | RAB9APOLBALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL8289725 | 0.86 | POLB (0.67) | RAB9APOLBPPARGNCOA2NCOA1 | |
| SCHEMBL1801190 | 0.86 | ALDH1A1 (0.68) | RAB9APOLBALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL1796979 | 0.85 | POLB (0.49) | RAB9APOLBPPARGNCOA2NCOA1 | |
| SCHEMBL1797621 | 0.85 | POLB (0.54) | RAB9APOLBALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL1800294 | 0.85 | PTPN1 (0.55) | RAB9APOLBALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7951806-B2 | Plasminogen activator inhibitor-1 inhibitor | RENASCIENCE CO., LTD. (JP) | 2011-05-31 | — | — | US | disclosed |
| US-20090124620-A1 | PLASMINOGEN ACTIVATOR INHIBITOR-1 INHIBITOR | RENASCIENCE CO., LTD. (JP) | 2009-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090124620-A1 | PLASMINOGEN ACTIVATOR INHIBITOR-1 INHIBITOR | SERPINE1, SERPINC1, SERPINB1 | RAB9A 2391/4885POLB 2674/4885PPARG 2036/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.