Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.56 |
| ▸ | GRM5 | P41594 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PLK1 | P53350 | 7/20 | 0.44 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.44 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.44 |
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.42 |
| ▸ | STAMBP | O95630 | 1/20 | 0.42 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.42 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24470049 | 0.81 | MPO (0.48) | HDAC6HDAC1HTTCA2 | |
| SCHEMBL7962334 | 0.80 | BAZ2B (0.74) | BAZ2BGRM5HDAC6HDAC2HDAC8 | |
| SCHEMBL13451410 | 0.78 | BAZ2B (0.57) | BAZ2BGRM5HDAC6HDAC2HDAC8 | |
| SCHEMBL3952478 | 0.78 | HDAC6 (0.72) | BAZ2BGRM5HDAC6HDAC2HDAC8 | |
| SCHEMBL13184552 | 0.78 | BAZ2B (0.57) | BAZ2BGRM5HDAC6HDAC2HDAC8 | |
| SCHEMBL8219501 | 0.78 | KCNJ1 (0.46) | HDAC6HDAC1HPGDTSHRSMN1; SMN2 | |
| SCHEMBL27909687 | 0.77 | RXFP1 (0.44) | HDAC6HDAC1HPGDHTTSMN1; SMN2 | |
| SCHEMBL4918065 | 0.77 | MAPK1 (0.65) | TSHRHPGDSCA2 | |
| SCHEMBL29670483 | 0.77 | MAPK1 (0.65) | TSHRHPGDSCA2 | |
| SCHEMBL103123 | 0.77 | RAB9A (0.61) | BAZ2BSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2718279-B1 | NOVEL COMPOUNDS AS MODULATORS OF GPR-119 | RHIZEN PHARMACEUTICALS SA (CH) | 2016-08-10 | — | — | EP | disclosed |