Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.74 |
| ▸ | P4HTM | Q9NXG6 | 4/20 | 0.57 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | GRM5 | P41594 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.47 |
| ▸ | STAMBP | O95630 | 1/20 | 0.47 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.47 |
| ▸ | PLK1 | P53350 | 5/20 | 0.47 |
| ▸ | HPGDS | O60760 | 2/20 | 0.46 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.46 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1542986 | 0.86 | BAZ2B (1.00) | BAZ2BP4HTMP4HA1MAPTGRM5 | |
| SCHEMBL15507078 | 0.84 | BAZ2B (0.79) | BAZ2BP4HTMP4HA1MAPTGRM5 | |
| SCHEMBL24976756 | 0.83 | BAZ2B (0.72) | BAZ2BP4HTMMAPTSMN1; SMN2HPGDS | |
| SCHEMBL24358015 | 0.83 | BAZ2B (0.55) | BAZ2BP4HTMP4HA1MAPTGRM5 | |
| SCHEMBL13184552 | 0.82 | BAZ2B (0.57) | BAZ2BP4HTMP4HA1GRM5HDAC6 | |
| SCHEMBL3952478 | 0.82 | HDAC6 (0.72) | BAZ2BGRM5HDAC6HDAC2HDAC8 | |
| SCHEMBL13451410 | 0.82 | BAZ2B (0.57) | BAZ2BGRM5HDAC6HDAC2HDAC8 | |
| SCHEMBL20057794 | 0.81 | BAZ2B (0.68) | BAZ2BMAPTGRM5SMN1; SMN2HPGDS | |
| SCHEMBL103123 | 0.80 | RAB9A (0.61) | BAZ2BMAPTSMN1; SMN2 | |
| SCHEMBL259496 | 0.80 | HDAC6 (0.70) | BAZ2BGRM5HDAC6HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187928-B1 | TREATING FUNGAL DISEASES | THE ROCKEFELLER UNIVERSITY | 2001-02-13 | — | — | US | disclosed |
| US-6087510-A | Method of use of imidazolium cations | THE ROCKEFELLER UNIVERSITY (US) | 2000-07-11 | — | — | US | disclosed |
| US-5874587-A | FLUORESCENCE | THE ROCKEFELLER UNIVERSITY (US) | 1999-02-23 | — | — | US | disclosed |