Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.32 |
| ▸ | IL1R1 | P14778 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17995042 | 0.96 | KDM4E (0.47) | KDM4EATML3MBTL1JAK2JAK3 | |
| SCHEMBL24703493 | 0.94 | KDM4E (0.49) | KDM4EATML3MBTL1JAK2JAK3 | |
| SCHEMBL17995030 | 0.93 | KDM4E (0.44) | KDM4EATML3MBTL1JAK2JAK3 | |
| SCHEMBL17995017 | 0.93 | KDM4E (0.44) | KDM4EATML3MBTL1JAK2JAK3 | |
| SCHEMBL17995001 | 0.93 | KDM4E (0.47) | KDM4EATML3MBTL1JAK2JAK3 | |
| SCHEMBL17995018 | 0.93 | KDM4E (0.50) | KDM4EATML3MBTL1JAK2JAK3 | |
| SCHEMBL20276575 | 0.93 | KDM4E (0.49) | KDM4EATML3MBTL1JAK2JAK3 | |
| SCHEMBL17995022 | 0.92 | ATM (0.42) | KDM4EATML3MBTL1JAK2JAK3 | |
| SCHEMBL22722268 | 0.91 | KDM4E (0.55) | KDM4EATML3MBTL1KMT2AMEN1 | |
| SCHEMBL25635033 | 0.91 | KDM4E (0.58) | KDM4EATML3MBTL1JAK2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240228523-A1 | Metal complexes | UDC IRELAND LTD (IE) | 2024-07-11 | — | — | US | disclosed |
| US-20240228523-A1 | Metal complexes | UDC IRELAND LTD (IE) | 2024-07-11 | — | — | US | disclosed |
| WO-2024133211-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2024-06-27 | — | — | WO | disclosed |
| US-10177316-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2019-01-08 | — | — | US | disclosed |
| US-20160233435-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2016-08-11 | — | — | US | disclosed |
| US-20160233435-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2016-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240228523-A1 | Metal complexes | MCU, IMMT, SOD1 | KDM4E 4540/4885ATM 4257/4885L3MBTL1 3190/4885 |
| US-20160233435-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | OSBP, OSBPL3, OSBP2 | KDM4E 4338/4885ATM 4180/4885L3MBTL1 808/4885 |
| US-10177316-B2 | Organic electroluminescent materials and devices | OSBP, OSBPL3, OSBP2 | KDM4E 4338/4885ATM 4180/4885L3MBTL1 808/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.