Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | RIPK2 | O43353 | 3/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7263096 | 0.72 | HPGD (0.33) | HPGDSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7113251 | 0.70 | SMN1; SMN2 (0.50) | HPGDSMN1; SMN2RIPK2 | |
| SCHEMBL21721135 | 0.58 | SMN1; SMN2 (0.43) | HPGDSMN1; SMN2 | |
| SCHEMBL21719694 | 0.58 | SMN1; SMN2 (0.32) | HPGDSMN1; SMN2 | |
| SCHEMBL21721450 | 0.57 | SMN1; SMN2 (0.31) | HPGDSMN1; SMN2RIPK2SRC | |
| SCHEMBL21721136 | 0.57 | HPGD (0.34) | HPGDSMN1; SMN2 | |
| SCHEMBL21721131 | 0.57 | HPGD (0.31) | HPGDSMN1; SMN2 | |
| SCHEMBL21721162 | 0.55 | SMN1; SMN2 (0.33) | HPGDSMN1; SMN2RIPK2SRC | |
| SCHEMBL21721451 | 0.55 | SMN1; SMN2 (0.41) | HPGDSMN1; SMN2RIPK2SRC | |
| SCHEMBL21721129 | 0.55 | SMN1; SMN2 (0.41) | HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1011619-B2 | DYEING COMPOSITION FOR KERATIN FIBRES | OREAL (FR) | 2012-07-04 | — | — | EP | claimed |
| EP-1345580-B9 | COMPOSITION FOR OXIDATION DYEING OF KERATINOUS FIBRES COMPRISING A DIAMINO PYRAZOLE AND A CARBONYL COMPOUND | OREAL (FR) | 2009-11-25 | — | — | EP | claimed |
| EP-1345580-B1 | COMPOSITION FOR OXIDATION DYEING OF KERATINOUS FIBRES COMPRISING A DIAMINO PYRAZOLE AND A CARBONYL COMPOUND | OREAL (FR) | 2006-06-07 | — | — | EP | claimed |
| EP-1011619-B1 | DYEING COMPOSITION FOR KERATIN FIBRES | OREAL (FR) | 2005-09-14 | — | — | EP | claimed |
| EP-1345579-B1 | COMPOSITION FOR OXIDATION DYEING OF KERATINOUS FIBRES COMPRISING AN AMINO PYRAZOLE AND A MINERAL COMPOUND | OREAL (FR) | 2005-06-29 | — | — | EP | claimed |
| US-20040237219-A1 | Composition for oxidation dyeing of keratinous fibres comprising at least a 4,5 or 3,4-diamino pyrazole or a triamino pyrazole and at least a particular cellulose compound, and dyeing method | L'OREAL (FR) | 2004-12-02 | — | — | US | claimed |
| US-6780203-B1 | DIAMINOPYRAZOLE DERIVATIVE OXIDATION HAIR DYE AND 3-AMINO-2-CHLORO-6- METHYLPHENOL OR SALT COUPLER | L'ORéAL S.A. (FR) | 2004-08-24 | — | — | US | claimed |
| US-20040088800-A1 | Composition for the oxidation dyeing of keratinous fibres comprising a diamino pyrazole and a carbonyl compound | L'OREAL (FR) | 2004-05-13 | — | — | US | claimed |
| US-20040074014-A1 | Composition for oxidation dyeing of keratinous fibres comprising an amino pyrazole and a mineral compound | L'OREAL (FR) | 2004-04-22 | — | — | US | claimed |
| US-6645258-B2 | Oxidation base selected from a 3-substituted 4,5-diaminopyrazoles; reacting | L'OREAL, S.A. (FR) | 2003-11-11 | — | — | US | claimed |
| US-20030019051-A9 | Composition for dyeing keratin fibers which contain at least one diaminopyrazole, dyeing process, novel diaminopyrazoles and process for their preparation | L'OREAL | 2003-01-30 | — | — | US | claimed |
| EP-1233744-A1 | COLOURING AGENT FOR KERATIN CONTAINING FIBRES | Henkel Kommanditgesellschaft auf Aktien (DE) | 2002-08-28 | — | — | EP | claimed |
| US-20020050013-A1 | Composition for dyeing keratin fibers which contain at least one diaminopyrazole, dyeing process, novel diaminopyrazoles and process for their preparation | L'OREAL | 2002-05-02 | — | — | US | claimed |
| US-6338741-B1 | 3-SUBSTITUTED 4,5-DIAMINOPYRAZOLES, OXIDATION HAIR DYES, STRONG COLORATION IN SHADES RANGING FROM RED TO BLUE | L'OREAL (FR) | 2002-01-15 | — | — | US | claimed |
| WO-2001034104-A1 | COLOURING AGENT FOR KERATIN CONTAINING FIBRES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2001-05-17 | — | — | WO | claimed |
| US-6099592-A | SPECIFIED 3-SUBSTITUTED 4,5-DIAMINOPYRAZOLES SUCH AS 1-BENZYL-4,5-DIAMINO-3-METHYLPYRAZOLE AS OXIDATION DYE PRECURSORS; USE TO OBTAIN DYE COMPOSITIONS LEADING TO STRONG COLORATIONS, IN SHADES RANGING FROM RED TO BLUE | L'OREAL (FR) | 2000-08-08 | — | — | US | claimed |
| EP-0740931-B1 | Compositions for dyeing keratinic fibers containing diaminopyrazoles, process for dyeing, diaminopyrazoles and process for their preparation | OREAL (FR) | 1997-08-20 | — | — | EP | claimed |
| EP-1542647-B1 | Use of hair colouring products comprising 5,6-dihydroxyindoline or a physiologically acceptable salt thereof | HENKEL AG & CO KGAA (DE) | 2014-09-24 | — | — | EP | disclosed |
| WO-2001047475-A2 | AGENT FOR DYEING KERATIN CONTAINING FIBERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2001-07-05 | — | — | WO | disclosed |
| US-6099592-A | SPECIFIED 3-SUBSTITUTED 4,5-DIAMINOPYRAZOLES SUCH AS 1-BENZYL-4,5-DIAMINO-3-METHYLPYRAZOLE AS OXIDATION DYE PRECURSORS; USE TO OBTAIN DYE COMPOSITIONS LEADING TO STRONG COLORATIONS, IN SHADES RANGING FROM RED TO BLUE | L'OREAL (FR) | 2000-08-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020050013-A1 | Composition for dyeing keratin fibers which contain at least one diaminopyrazole, dyeing process, novel diaminopyrazoles and process for their preparation | KRT18, DSP, TUBB3 | HPGD 672/4885SMN1; SMN2 4233/4885RIPK2 1722/4885 |
| US-20030019051-A9 | Composition for dyeing keratin fibers which contain at least one diaminopyrazole, dyeing process, novel diaminopyrazoles and process for their preparation | KRT18, DSP, TUBB3 | HPGD 672/4885SMN1; SMN2 4233/4885RIPK2 1722/4885 |
| US-20040237219-A1 | Composition for oxidation dyeing of keratinous fibres comprising at least a 4,5 or 3,4-diamino pyrazole or a triamino pyrazole and at least a particular cellulose compound, and dyeing method | KRT18, TUBB3, PPOX | HPGD 583/4885SMN1; SMN2 4815/4885RIPK2 3099/4885 |
| US-20040074014-A1 | Composition for oxidation dyeing of keratinous fibres comprising an amino pyrazole and a mineral compound | KRT18, TUBB3, COX5A | HPGD 379/4885SMN1; SMN2 4794/4885RIPK2 3235/4885 |
| US-20040088800-A1 | Composition for the oxidation dyeing of keratinous fibres comprising a diamino pyrazole and a carbonyl compound | KRT18, TUBB3, COX5A | HPGD 337/4885SMN1; SMN2 4695/4885RIPK2 1871/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.