Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 4/20 | 0.55 |
| ▸ | ABL1 | P00519 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CPS1 | P31327 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21274571 | 0.88 | HPGD (0.52) | P2RX3MAOBSLC6A4SLC6A3NPC1 | |
| SCHEMBL365782 | 0.87 | SCN9A (0.52) | P2RX3ABL1TDP1SLC6A4CPS1 | |
| SCHEMBL23386692 | 0.86 | XDH (0.51) | P2RX3TDP1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL22406928 | 0.85 | CYP11B1 (0.48) | P2RX3MAOAMAOBLMNACYP11B1 | |
| SCHEMBL22407068 | 0.84 | MAOB (0.68) | P2RX3MAOAMAOBLMNACYP11B1 | |
| SCHEMBL1350185 | 0.84 | ABL1 (0.64) | ABL1SLC6A4SLC6A3CYP11B1CYP11B2 | |
| SCHEMBL22406882 | 0.83 | MAOB (0.46) | P2RX3MAOAMAOBLMNACYP11B1 | |
| SCHEMBL11540801 | 0.82 | MAOB (0.48) | P2RX3MAOAMAOBLMNACYP11B1 | |
| SCHEMBL28665319 | 0.81 | AR (0.51) | P2RX3ABL1TDP1SLC6A4SLC6A3 | |
| SCHEMBL5255602 | 0.81 | MAOB (0.52) | P2RX3MAOAMAOBLMNACYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3059224-B1 | 4-AMINOMETHYLBENZOIC ACID DERIVATIVE | TOA EIYO LTD (JP) | 2019-03-20 | — | — | EP | disclosed |
| US-9714213-B2 | 4-aminomethylbenzoic acid derivative | TOA EIYO LTD. (JP) | 2017-07-25 | — | — | US | disclosed |
| US-20160264514-A1 | 4-AMINOMETHYLBENZOIC ACID DERIVATIVE | TOA EIYO LTD. (JP) | 2016-09-15 | — | — | US | disclosed |
| EP-3059224-A1 | 4-AMINOMETHYLBENZOIC ACID DERIVATIVE | TOA Eiyo Ltd. (JP) | 2016-08-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160264514-A1 | 4-AMINOMETHYLBENZOIC ACID DERIVATIVE | ALDH7A1, CYP2B6, CYP2A6 | P2RX3 4577/4885ABL1 99/4885MAOA 154/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.