Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.43 |
| ▸ | CCNC | P24863 | 1/20 | 0.43 |
| ▸ | CDK8 | P49336 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14637734 | 0.85 | ALDH1A1 (0.47) | MAOBMAOACCNCCDK8MMP1 | |
| SCHEMBL22407068 | 0.83 | MAOB (0.68) | MAOBMAOAP2RX3CYP11B1CYP11B2 | |
| SCHEMBL29993560 | 0.82 | KCNH2 (0.49) | MAOBMAOACYP11B1CYP11B2KCNH2 | |
| SCHEMBL8022080 | 0.82 | KCNH2 (0.49) | MAOBMAOACYP11B1CYP11B2KCNH2 | |
| SCHEMBL27604216 | 0.82 | MMP1 (0.43) | MAOBMAOACCNCCDK8MMP1 | |
| SCHEMBL28039336 | 0.82 | AR (0.50) | MAOBMAOACCNCCDK8MMP1 | |
| SCHEMBL17996051 | 0.81 | P2RX3 (0.55) | MAOBMAOAP2RX3CYP11B1CYP11B2 | |
| SCHEMBL28037947 | 0.80 | CCNC (0.41) | MAOBMAOACCNCCDK8MMP1 | |
| SCHEMBL2842833 | 0.80 | CPS1 (0.58) | LMNA | |
| SCHEMBL28672489 | 0.79 | CCNC (0.50) | MAOBMAOACCNCCDK8KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0844993-B1 | PESTICIDAL INDAZOLE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2007-09-26 | — | — | EP | disclosed |
| US-5935908-A | PLANT GROWTH REGULATOR | NOVARTIS CROP PROTECTION, INC. (US) | 1999-08-10 | — | — | US | disclosed |
| EP-0844993-A2 | PESTICIDAL INDAZOLE DERIVATIVES | Novartis AG (CH) | 1998-06-03 | — | — | EP | disclosed |
| WO-1997007103-A2 | PESTICIDAL INDAZOLE DERIVATIVES | NOVARTIS AG (CH) | 1997-02-27 | — | — | WO | disclosed |