Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TDP2 | O95551 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17997070 | 0.97 | KDM4E (0.41) | KDM4EALDH1A1GLAGAAPTGER4 | |
| SCHEMBL17996908 | 0.93 | TDP2 (0.36) | KDM4EALDH1A1GLAGAAMAPT | |
| SCHEMBL17996906 | 0.91 | KDM4E (0.34) | KDM4EALDH1A1GLAGAAPTGER4 | |
| SCHEMBL17996911 | 0.85 | PTGER4 (0.38) | KDM4EALDH1A1PTGER4MAPTL3MBTL1 | |
| SCHEMBL17996904 | 0.85 | KDM4E (0.47) | KDM4EALDH1A1GAAMAPTL3MBTL1 | |
| SCHEMBL17993488 | 0.84 | KDM4E (0.51) | KDM4EALDH1A1GLAGAAPTGER4 | |
| SCHEMBL17996902 | 0.81 | KDM4E (0.47) | KDM4EALDH1A1MAPTL3MBTL1ATM | |
| SCHEMBL17996910 | 0.78 | KDM4E (0.42) | KDM4EALDH1A1GAAPTGER4MAPT | |
| SCHEMBL21890337 | 0.78 | KDM4E (0.49) | KDM4EALDH1A1GAAMAPTL3MBTL1 | |
| SCHEMBL17996907 | 0.78 | KDM4E (0.44) | KDM4EALDH1A1GAAMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016125110-A1 | BISIMIDAZOLODIAZOCINES | IDEMITSU KOSAN CO., LTD. (JP) | 2016-08-11 | — | — | WO | disclosed |