Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | TDP2 | O95551 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17996905 | 0.97 | KDM4E (0.39) | KDM4EALDH1A1GLAGAAL3MBTL1 | |
| SCHEMBL17996908 | 0.89 | TDP2 (0.36) | KDM4EALDH1A1GLAGAAL3MBTL1 | |
| SCHEMBL17996906 | 0.87 | KDM4E (0.34) | KDM4EALDH1A1GLAGAAL3MBTL1 | |
| SCHEMBL17996902 | 0.84 | KDM4E (0.47) | KDM4EALDH1A1L3MBTL1ATMMAPT | |
| SCHEMBL17996911 | 0.82 | PTGER4 (0.38) | KDM4EALDH1A1L3MBTL1ATMPTGER4 | |
| SCHEMBL17996904 | 0.81 | KDM4E (0.47) | KDM4EALDH1A1GAAL3MBTL1ATM | |
| SCHEMBL17996907 | 0.80 | KDM4E (0.44) | KDM4EALDH1A1GAAL3MBTL1ATM | |
| SCHEMBL17993488 | 0.79 | KDM4E (0.51) | KDM4EALDH1A1GLAGAAPTGER4 | |
| SCHEMBL19702132 | 0.78 | KDM4E (0.46) | KDM4EL3MBTL1ATMTDP2 | |
| SCHEMBL21890337 | 0.78 | KDM4E (0.49) | KDM4EALDH1A1GAAL3MBTL1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016125110-A1 | BISIMIDAZOLODIAZOCINES | IDEMITSU KOSAN CO., LTD. (JP) | 2016-08-11 | — | — | WO | disclosed |