Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | ERN1 | O75460 | 1/20 | 0.31 |
| ▸ | SLC5A2 | P31639 | 3/20 | 0.31 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.31 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.31 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.30 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 2/20 | 0.30 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.30 |
| ▸ | QPCT | Q16769 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL439595 | 0.97 | ERN1 (0.34) | TDP1POLBL3MBTL1TP53MAPT | |
| SCHEMBL15617857 | 0.94 | ERN1 (0.36) | TDP1CHEK1ERN1SLC5A2CRHR1 | |
| SCHEMBL469128 | 0.90 | ERN1 (0.35) | TDP1POLBL3MBTL1TP53CHEK1 | |
| SCHEMBL14692897 | 0.90 | EGFR (0.36) | ALDH1A1UCHL1TAOK1TAOK3EGFR | |
| SCHEMBL13681229 | 0.90 | TUBB4A (0.33) | TDP1POLBL3MBTL1MAPTALDH1A1 | |
| SCHEMBL437667 | 0.89 | L3MBTL1 (0.35) | TDP1POLBL3MBTL1TP53MAPT | |
| SCHEMBL12404417 | 0.86 | GPR88 (0.37) | CHEK1ERN1CRHR1 | |
| SCHEMBL12472285 | 0.85 | FAAH (0.36) | TDP1POLBL3MBTL1CHEK1ERN1 | |
| SCHEMBL10090912 | 0.84 | KDM4E (0.34) | TDP1POLBL3MBTL1MAPTALDH1A1 | |
| SCHEMBL279198 | 0.83 | TUBB4A (0.36) | TDP1POLBL3MBTL1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9500968-B2 | Addition of non-networked hole transport molecule to fluorinated structured organic film for improved corona resistance | XEROX CORPORATION (US) | 2016-11-22 | — | — | US | disclosed |
| US-20160231660-A1 | ADDITION OF NON-NETWORKED HOLE TRANSPORT MOLECULE TO FLUORINATED STRUCTURED ORGANIC FILM FOR IMPROVED CORONA RESISTANCE | XEROX CORPORATION | 2016-08-11 | — | — | US | disclosed |