Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.38 |
| ▸ | RXRA | P19793 | 4/20 | 0.34 |
| ▸ | RXRB | P28702 | 4/20 | 0.34 |
| ▸ | RXRG | P48443 | 3/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 2/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | IKBKB | O14920 | 1/20 | 0.31 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.31 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19441759 | 0.89 | RXRA (0.40) | RXRARXRBRXRGKIF11P2RX1 | |
| Hydrochloric Acid SCHEMBL3145406 | 0.81 | ALDH1A1 (0.33) | RXRARXRB | |
| SCHEMBL7196197 | 0.80 | SLC22A2 (0.32) | RXRARXRB | |
| SCHEMBL17996978 | 0.79 | MEN1 (0.43) | RAPGEF4KIF11IKBKB | |
| SCHEMBL29738939 | 0.76 | SLC22A2 (0.46) | — | |
| SCHEMBL19888148 | 0.75 | BCHE (0.41) | MAPTKIF11 | |
| SCHEMBL10005293 | 0.73 | TSHR (0.44) | NOTUMMAPTKIF11 | |
| Hydrochloric Acid SCHEMBL14937435 | 0.71 | TSHR (0.42) | NOTUMMAPTKIF11 | |
| SCHEMBL19892477 | 0.71 | KIF11 (0.48) | KIF11 | |
| SCHEMBL24518592 | 0.70 | RXRA (0.48) | RAPGEF4RXRARXRBRXRGNOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230374230-A1 | CROSSLINKED GEL FORMULATION | ESSILOR INTERNATIONAL (FR) | 2023-11-23 | — | — | US | disclosed |
| US-20230220274-A1 | ELECTROCHROMIC SOLUTION | ESSILOR INTERNATIONAL (FR) | 2023-07-13 | — | — | US | disclosed |
| US-9841652-B2 | Electrochromic composition | ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) | 2017-12-12 | — | — | US | disclosed |
| US-9785030-B2 | Electrochromic composition | ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) | 2017-10-10 | — | — | US | disclosed |
| US-20160282694-A1 | ELECTROCHROMIC COMPOSITION | ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) | 2016-09-29 | — | — | US | disclosed |
| US-20160231636-A1 | ELECTROCHROMIC COMPOSITION | ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) | 2016-08-11 | — | — | US | disclosed |