SCHEMBL179972

SCHEMBL179972

CC(=NNc1ccccn1)c1ccc(O)cc1O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NCOA1 Q15788 1/20 0.54
NCOA3 Q9Y6Q9 1/20 0.54
GAA P10253 8/20 0.52
RAB9A P51151 5/20 0.52
SMN1; SMN2 Q16637 5/20 0.52
NPC1 O15118 4/20 0.52
MAPT P10636 9/20 0.51
MEN1 O00255 4/20 0.51
KMT2A Q03164 4/20 0.51
HTT P42858 1/20 0.50
KDM4E B2RXH2 2/20 0.48
ALDH1A1 P00352 1/20 0.48
LMNA P02545 1/20 0.48
GFER P55789 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.45
NFKB1 P19838 1/20 0.45
NFKB2 Q00653 1/20 0.45
RELA Q04206 1/20 0.45
CCR6 P51684 2/20 0.45
CXCR5 P32302 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12570766 1.00 NCOA1 (0.54) NCOA1NCOA3GAARAB9ASMN1; SMN2
SCHEMBL180203 0.78 MAPT (0.61) GAARAB9ASMN1; SMN2MAPTMEN1
SCHEMBL180204 0.78 MAPT (0.61) GAARAB9ASMN1; SMN2MAPTMEN1
SCHEMBL12720808 0.76 NPC1 (0.69) GAARAB9ASMN1; SMN2NPC1MAPT
SCHEMBL20101098 0.74 MAPT (0.73) GAARAB9ASMN1; SMN2NPC1MAPT
SCHEMBL6715793 0.74 PAX8 (0.67) GAARAB9ASMN1; SMN2NPC1MAPT
SCHEMBL20101085 0.74 PAX8 (0.67) GAARAB9ASMN1; SMN2NPC1MAPT
SCHEMBL6715790 0.74 PAX8 (0.67) GAARAB9ASMN1; SMN2NPC1MAPT
SCHEMBL1973299 0.73 RAB9A (0.59) GAARAB9ASMN1; SMN2NPC1MAPT
SCHEMBL2269809 0.72 NPC1 (0.69) GAARAB9ASMN1; SMN2NPC1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2402081-A1 AMMONIA DECOMPOSITION CATALYST Hitachi Zosen Corporation (JP) 2012-01-04 EP disclosed
US-7960501-B2 Catalyst using hydrazone compound, hydrazone polymer compound, and catalyst using hydrazone polymer compound TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) 2011-06-14 US disclosed
US-7951903-B2 Hydrazone compound, hydrazone compound for forming complex, ligand for forming metal complex, and monomer for manufacturing polymer compound TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) 2011-05-31 US disclosed
US-20090062506-A1 CATALYST USING HYDRAZONE COMPOUND, HYDRAZONE POLYMER COMPOUND, AND CATALYST USING HYDRAZONE POLYMER COMPOUND TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) 2009-03-05 US disclosed
US-20090062507-A1 HYDRAZONE COMPOUND, HYDRAZONE COMPOUND FOR FORMING COMPLEX, LIGAND FOR FORMING METAL COMPLEX, AND MONOMER FOR MANUFACTURING POLYMER COMPOUND TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) 2009-03-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090062507-A1 HYDRAZONE COMPOUND, HYDRAZONE COMPOUND FOR FORMING COMPLEX, LIGAND FOR FORMING METAL COMPLEX, AND MONOMER FOR MANUFACTURING POLYMER COMPOUND PBRM1, AP1M1, PUM1 NCOA1 1442/4885NCOA3 3440/4885GAA 3543/4885
US-20090062506-A1 CATALYST USING HYDRAZONE COMPOUND, HYDRAZONE POLYMER COMPOUND, AND CATALYST USING HYDRAZONE POLYMER COMPOUND PKD1, HDAC1, HDAC11 NCOA1 2006/4885NCOA3 4258/4885GAA 1154/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.