Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 11/20 | 0.59 |
| ▸ | NPC1 | O15118 | 9/20 | 0.59 |
| ▸ | GAA | P10253 | 7/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.59 |
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.45 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7831618 | 0.85 | RAB9A (0.56) | RAB9ANPC1GAASMN1; SMN2MAPT | |
| SCHEMBL6715793 | 0.82 | PAX8 (0.67) | RAB9ANPC1GAASMN1; SMN2MAPT | |
| SCHEMBL15315184 | 0.82 | RAB9A (0.60) | RAB9ANPC1GAASMN1; SMN2MAPT | |
| SCHEMBL28689206 | 0.82 | RAB9A (0.54) | RAB9ANPC1GAASMN1; SMN2MAPT | |
| SCHEMBL20101085 | 0.82 | PAX8 (0.67) | RAB9ANPC1GAASMN1; SMN2MAPT | |
| SCHEMBL6715790 | 0.82 | PAX8 (0.67) | RAB9ANPC1GAASMN1; SMN2MAPT | |
| SCHEMBL20101098 | 0.82 | MAPT (0.73) | RAB9ANPC1GAASMN1; SMN2MAPT | |
| SCHEMBL15267189 | 0.77 | KDM4E (0.58) | RAB9ANPC1GAASMN1; SMN2MAPT | |
| SCHEMBL12727643 | 0.74 | TOP2A (0.59) | RAB9ANPC1GAASMN1; SMN2MAPT | |
| SCHEMBL23550666 | 0.74 | LMNA (0.55) | RAB9ANPC1GAASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130165350-A1 | SURFACE LINKERS FOR ARRAY SYNTHESIS | AFFYMETRIX, INC. (US) | 2013-06-27 | — | — | US | disclosed |
| US-20110143967-A1 | SURFACE MODIFICATIONS AND METHODS FOR THEIR SYNTHESIS AND USE | AFFYMETRIX, INC. | 2011-06-16 | — | — | US | disclosed |
| US-20110143966-A1 | Surface Modifications and Methods for their Synthesis and Use | AFFYMETRIX, INC. (US) | 2011-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110143966-A1 | Surface Modifications and Methods for their Synthesis and Use | SDC4, SDC1, SDC2 | RAB9A 4053/4885NPC1 4368/4885GAA 2346/4885 |
| US-20110143967-A1 | SURFACE MODIFICATIONS AND METHODS FOR THEIR SYNTHESIS AND USE | SDC4, SDC1, SDC2 | RAB9A 4053/4885NPC1 4368/4885GAA 2346/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.