Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.73 |
| ▸ | RAB9A | P51151 | 7/20 | 0.73 |
| ▸ | GAA | P10253 | 6/20 | 0.73 |
| ▸ | NPC1 | O15118 | 6/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.73 |
| ▸ | MEN1 | O00255 | 3/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.73 |
| ▸ | HTT | P42858 | 2/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | KDM6B | O15054 | 1/20 | 0.46 |
| ▸ | TET3 | O43151 | 1/20 | 0.46 |
| ▸ | KDM4A | O75164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6715790 | 0.83 | PAX8 (0.67) | MAPTRAB9AGAANPC1SMN1; SMN2 | |
| SCHEMBL20101085 | 0.83 | PAX8 (0.67) | MAPTRAB9AGAANPC1SMN1; SMN2 | |
| SCHEMBL6715793 | 0.83 | PAX8 (0.67) | MAPTRAB9AGAANPC1SMN1; SMN2 | |
| SCHEMBL15267189 | 0.82 | KDM4E (0.58) | MAPTRAB9AGAANPC1SMN1; SMN2 | |
| SCHEMBL1973299 | 0.82 | RAB9A (0.59) | MAPTRAB9AGAANPC1SMN1; SMN2 | |
| SCHEMBL21764330 | 0.79 | MAPT (0.52) | MAPTRAB9AGAANPC1SMN1; SMN2 | |
| SCHEMBL7831618 | 0.79 | RAB9A (0.56) | MAPTRAB9AGAANPC1SMN1; SMN2 | |
| SCHEMBL20101080 | 0.77 | KDM4E (0.72) | MAPTRAB9AGAANPC1SMN1; SMN2 | |
| SCHEMBL4926318 | 0.77 | KDM4E (0.72) | MAPTRAB9AGAANPC1SMN1; SMN2 | |
| SCHEMBL28689206 | 0.76 | RAB9A (0.54) | MAPTRAB9AGAANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018081612-A1 | COMPOUNDS AND METHODS FOR TREATING CANCER | ACTAVALON, INC. (US) | 2018-05-03 | — | — | WO | disclosed |