Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 10/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.44 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.44 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1799720 | 0.87 | KMT2A (0.61) | MEN1KMT2AMAPTNPC1GRIN2C | |
| SCHEMBL1894620 | 0.85 | MEN1 (0.46) | MEN1KMT2AMAPTNPC1GRIN2C | |
| SCHEMBL1954895 | 0.76 | ANO1 (0.54) | MEN1KMT2AMAPTNPC1ALDH1A1 | |
| SCHEMBL1907629 | 0.76 | ABL1 (0.56) | MEN1KMT2AMAPTCASP3SENP8 | |
| SCHEMBL12271566 | 0.72 | CASP3 (0.56) | MEN1KMT2AMAPTNPC1GRIN2C | |
| SCHEMBL21259065 | 0.72 | MEN1 (0.73) | MEN1KMT2ANPC1GRIN2CALDH1A1 | |
| SCHEMBL1954030 | 0.71 | ANO1 (0.63) | MEN1KMT2AANO1 | |
| SCHEMBL1954473 | 0.71 | MEN1 (0.55) | MEN1KMT2AMAPTNPC1ALDH1A1 | |
| SCHEMBL15258591 | 0.71 | CASP3 (0.56) | MEN1KMT2ANPC1GRIN2CRAB9A | |
| SCHEMBL28760465 | 0.71 | ALDH1A1 (0.54) | MEN1KMT2AMAPTALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010027875-A2 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | CALCIMEDICA INC. (US) | 2010-03-11 | — | — | WO | disclosed |