Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.34 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17997464 | 0.92 | PTGS2 (0.44) | MAPTSMN1; SMN2GAAALDH1A1ALOX12 | |
| SCHEMBL17997460 | 0.92 | PTGS2 (0.41) | MAPTSMN1; SMN2GAAALDH1A1ALOX12 | |
| SCHEMBL17997449 | 0.91 | PTGS2 (0.48) | MAPTSMN1; SMN2GAAALDH1A1ALOX12 | |
| SCHEMBL17997454 | 0.89 | RAPGEF4 (0.43) | MAPTSMN1; SMN2ALDH1A1HTTJAK2 | |
| SCHEMBL17997456 | 0.88 | PTGS2 (0.39) | MAPTSMN1; SMN2GAAALDH1A1ALOX12 | |
| SCHEMBL13007202 | 0.87 | PTGS2 (0.51) | MAPTSMN1; SMN2GAAALDH1A1ALOX12 | |
| SCHEMBL14079198 | 0.83 | PTGS2 (0.44) | MAPTSMN1; SMN2GAAALDH1A1ALOX12 | |
| SCHEMBL22893442 | 0.83 | PTGS2 (0.44) | MAPTSMN1; SMN2GAAALDH1A1ALOX12 | |
| SCHEMBL17997457 | 0.81 | PTGS2 (0.50) | MAPTSMN1; SMN2GAAHTTRAB9A | |
| SCHEMBL17997452 | 0.78 | PTGS2 (0.57) | MAPTSMN1; SMN2ALDH1A1RAB9APTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160231658-A1 | ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND IMAGE FORMING APPARATUS | Konica Minolta, Inc. (JP) | 2016-08-11 | — | — | US | disclosed |